Patterns & Phenotypes
Expression patterns of FGF receptors in the developing mammalian cochlea
Version of Record online: 3 FEB 2010
Copyright © 2010 Wiley-Liss, Inc.
Volume 239, Issue 3, pages 1019–1026, March 2010
How to Cite
Hayashi, T., Ray, C. A., Younkins, C. and Bermingham-McDonogh, O. (2010), Expression patterns of FGF receptors in the developing mammalian cochlea. Dev. Dyn., 239: 1019–1026. doi: 10.1002/dvdy.22236
- Issue online: 11 FEB 2010
- Version of Record online: 3 FEB 2010
- Manuscript Accepted: 18 DEC 2009
- National Institutes of Health. Grant Numbers: DC005953, P30DC00466
- Hearing Regeneration Initiative
Additional Supporting Information may be found in the online version of this article.
|DVDY_22236_sm_supfig1.tif||28891K||Supp. Fig. S1. Fgfr expression in mouse embryos. To verify the specificity of the probes used for in situ hybridization, we tested them on sections of developing brain. Fgfr1, Fgfr2, and Fgfr3 are all highly expressed in the lateral ventricle, as reported in previous publications. Fgfr4 is not highly expressed in the brain, but is highly expressed in the extraocular muscles. Co, Cochlea; LV, lateral ventricle; L, lens; R, Retina; OM, ocular muscle. Scale bars = 100 μm.|
|DVDY_22236_sm_supfig2.tif||2780K||Supp. Fig. S2. Fgfr3 is expressed in the postnatal day (P) 21 cochlea. A,B: Sections of the mid-apical tunes of P21 cochlea. In B, the organ of Corti was photographed at the high magnification. The asterisks in B indicate the nuclei of the Deiters' cells. TM; tectorial membrane. OHC, outer hair cells; PCs, pillar cells; DCs, Deiters' cells. Scale bar = 100 μm in A, 50 μm in B.|
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