All authors contributed equally to this work.
Special Issue Reviews–A Peer Reviewed Forum
Understanding the role of asymmetric cell division in cancer using C. elegans
Article first published online: 5 FEB 2010
Copyright © 2010 Wiley-Liss, Inc.
Special Issue: Special Issue on Caenorhabditis elegans
Volume 239, Issue 5, pages 1378–1387, May 2010
How to Cite
Hyenne, V., Chartier, N. T. and Labbé, J.-C. (2010), Understanding the role of asymmetric cell division in cancer using C. elegans. Dev. Dyn., 239: 1378–1387. doi: 10.1002/dvdy.22237
- Issue published online: 13 APR 2010
- Article first published online: 5 FEB 2010
- Manuscript Accepted: 21 DEC 2009
- Canadian Cancer Society. Grant Number: 19378
- Canadian Institutes of Health Research. Grant Number: 158715
- asymmetric cell division;
- cell polarity;
- normal and cancer stem cells;
- Caenorhabditis elegans
Asymmetric cell division is an important process to generate cell diversity and maintain tissue homeostasis. Recent evidence suggests that this process may also be crucial to prevent tumor formation. In the past 30 years, the embryo of the nematode Caenorhabditis elegans has proven to be a very powerful model to study the molecular and cellular basis of asymmetric cell division. Understanding this process in Caenorhabditis elegans may thus lead to a better understanding of stem cell function and tumorigenesis in humans. Developmental Dynamics 239:1378–1387, 2010. © 2010 Wiley-Liss, Inc.