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Keywords:

  • spheroids;
  • tissue liquidity;
  • blood vessels;
  • dorsal aorta;
  • angiogenesis;
  • differential adhesion;
  • anastomosis

Abstract

Zebrafish Intrahepatic Biliary System: Confocal projection through the liver of a 5 day post-fertilization zebrafish larva immunostained with antibodies raised against the human multidrug resistance protein-1 (red), also known as Pglcyoprotein, an ABC transporter in the hepatocyte canalicular membrane, and a novel zebrafish epitope 2F11 (green) that recognizes biliary epithelial cells. Hepatocytes secrete bile through their canaliculus into the intrahepatic biliary duct network. 10 μm z-stack. From Lorent et al., Developmental Dynamics 239:398-406, 2010.