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Caenorhabditis elegans as a model for stem cell biology

  1. Pradeep M. Joshi1,
  2. Misty R. Riddle2,
  3. Nareg J.V. Djabrayan2,
  4. Joel H. Rothman1,2,*

Article first published online: 13 APR 2010

DOI: 10.1002/dvdy.22311

Issue

Developmental Dynamics

Developmental Dynamics

Special Issue: Special Issue on Caenorhabditis elegans

Volume 239, Issue 5, page spcone, May 2010

Additional Information

How to Cite

Joshi, P. M., Riddle, M. R., Djabrayan, N. J.V. and Rothman, J. H. (2010), Caenorhabditis elegans as a model for stem cell biology. Dev. Dyn., 239: spcone. doi: 10.1002/dvdy.22311

Author Information

  1. 1

    Neuroscience Research Institute, University of California Santa Barbara, Santa Barbara, California

  2. 2

    Department of Molecular, Cell and Developmental Biology, University of California Santa Barbara, Santa Barbara, California

*Neuroscience Research Institute, University of California Santa Barbara, Santa Barbara, CA 93106

Publication History

  1. Issue published online: 13 APR 2010
  2. Article first published online: 13 APR 2010
  3. Manuscript Accepted: 6 JUL 2009

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Keywords:

  • stem cells;
  • germline;
  • reprogramming;
  • transdifferentiation;
  • microRNA;
  • translational suppressors

Abstract

An adult transgenic C. elegans expressing membrane targeted GFP and mCherry::Histone 2B fusion proteins that demarcate the cell membrane boundaries and nuclei respectively. Strong expression is seen throughout the germline and perdures through embryonic development. From Joshi et al., Developmental Dynamics 239:1539–1554, 2010.

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