Additional Supporting Information may be found in the online version of this article.

DVDY_22463_sm_suppfig-S1.tif6194KSuppl. Fig. 1. Larvae at stage 35. They characteristically have apparent forelimb buds.
DVDY_22463_sm_suppfig-S2.tif8259KSuppl. Fig. 2. Digestive organs of a swimming larva (stage 59) showing an intense green fluorescence uniformly throughout the body. A, B: A ventral view of the animal after incision of the abdominal cavity. C, D: A magnified view of the internal organs. E-H: Isolated stomach (E, F) and intestine (G, H). The contents of the stomach and intestine were removed as well as possible. A, C, E, G: Bright-light image; B, D, F, H: Fluorescence image. Scale bars = 5mm (A, B), 2mm (C-H). The animal shown here was anesthetized in 0.1% FA100 (Tanabe, Japan) for ˜10 min, fixed in 4% paraformaldehyde in PBS solution for ˜1h at 4°C, and then dissected. The peristaltic movement of this green intestine (H), which was visible through the skin, is shown in Suppl. Movie 6.
DVDY_22463_sm_suppfig-S3.tif6862KSuppl. Fig. 3. Bones and muscles of a swimming larva (stage 59) showing an intense green fluorescence uniformly throughout the body. A forelimb of the animal shown in Suppl. Fig. 2 was examined here. The skin covering the forelimb was removed completely, and then the muscle of the upper arm was teased to expose a bone. The bone (arrow) and muscle fibers (arrowheads) exhibited an intense green fluorescence. Scale bars = 2mm.
DVDY_22463_sm_suppmovie-S1.wmv2021KSuppl. Movie 1. Swimming larva (stage 40) shown in Figure 4G, H.
DVDY_22463_sm_suppmovie-S2.wmv3912KSuppl. Movie 2. Swimming larva (stage 50).
DVDY_22463_sm_suppmovie-S3.wmv4069KSuppl. Movie 3. Head region of a swimming larva (stage 50). Dorsal view.
DVDY_22463_sm_suppmovie-S4.wmv5716KSuppl. Movie 4. Front limb of a swimming larva (stage 50).
DVDY_22463_sm_suppmovie-S5.wmv2455KSuppl. Movie 5. Beating heart of a swimming larva (stage 50).Ventral view.
DVDY_22463_sm_suppmovie-S6.wmv13263KSuppl. Movie 6. Moving intestine of a swimming larva (stage 59). Ventral view.
DVDY_22463_sm_suppmovie-S7.wmv5018KSuppl. Movie 7. Juvenile newt after metamorphosis.
DVDY_22463_sm_suppmovie-S8.wmv1537KSuppl. Movie 8. Head region of a juvenile shown in Figure 4I-L.
DVDY_22463_sm_suppmovie-S9.wmv2434KSuppl. Movie 9. Right eye of a juvenile (anesthetized) shown in Figure 4I-L.
DVDY_22463_sm_supptablesS1-S2.doc57KSupporting Tables S1–S2

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