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FilenameFormatSizeDescription
DVDY_22521_sm_suppfig1.tif1495KSupp. Fig. S1. Proliferation and apoptotic index in E14.5 AVC valves. A: Proliferation index in E14.5 atrio-ventricular valves. Y axes represents the number of proliferating (phospho-histone 3-positive) mesenchymal cells per 1,000 cells within AV valves. Horizontal black bars represent the average number of proliferating mesenchymal cells for each valve and genotype. B: Apoptotic index in E14.5 mitral valves. Y axes represents the number of apoptotic (activated caspase 3-positive) mesenchymal cells per 1,000 cells within the mitral valves. Horizontal black bars represent the average number of apoptotic mesenchymal cells.
DVDY_22521_sm_suppfig2.tif12571KSupp. Fig. S2. Distribution of endothelial markers in E14.5 and E16.5 control and Ltbp1L mutants. Immunostainings for endothelial markers Pecam1 (A, A') and claudin 5 (B, B') of the endothelium lining dorsal aorta in E14.5 control (A) and Ltbp1L null (A') embryos and E16.5 control (B) and Ltbp1L mutant (B') mitral valves. Arrows indicate endothelium.

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