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Special Issue Patterns & Phenotypes
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Dynamic expression of two thrombospondins during axolotl limb regeneration
Article first published online: 1 FEB 2011
DOI: 10.1002/dvdy.22548
Copyright © 2011 Wiley-Liss, Inc.
Issue
Developmental Dynamics
Special Issue: Special Issue on Limb Development
Volume 240, Issue 5, pages 1249–1258, May 2011
Additional Information
How to Cite
Whited, J. L., Lehoczky, J. A., Austin, C. A. and Tabin, C. J. (2011), Dynamic expression of two thrombospondins during axolotl limb regeneration. Dev. Dyn., 240: 1249–1258. doi: 10.1002/dvdy.22548
Publication History
- Issue published online: 20 APR 2011
- Article first published online: 1 FEB 2011
- Manuscript Accepted: 21 DEC 2010
Funded by
- NIH. Grant Numbers: F32 HD054082, F32 AR056149, R01 HD045499, R21 AR059884
REFERENCES
- , . 2004. The thrombospondins. Int J Biochem Cell Biol 36: 961–968.
- , , , , , , . 2003. Characterisation of Drosophila thrombospondin defines an early origin of pentameric thrombospondins. J Mol Biol 328: 479–494.
- , , , . 2002. The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice. Am J Pathol 161: 831–839.
- . 1987. The nerve dependence of amphibian limb regeneration. J Exp Biol 132: 79–91.
- , , . 2010. A transitional extracellular matrix instructs cell behavior during muscle regeneration. Dev Biol 344: 259–271.
- , , , , . 2007. AlphaPS2 integrin-mediated muscle attachment in Drosophila requires the ECM protein Thrombospondin. Mech Dev 124: 463–475.
- , , , , , . 2005. Limb regeneration in higher vertebrates: developing a roadmap. Anat Rec B New Anat 287: 14–24.
- , , , . 2003. Regeneration or scarring: an immunologic perspective. Dev Dyn 226: 268–279.Direct Link:
- . 1974. Trapped fingers and amputated finger tips in children. J Pediatr Surg 9: 853–858.
- . 1989. Organization of connective tissue patterns by dermal fibroblasts in the regenerating axolotl limb. Development 105: 585–593.
- , , , , , . 2005. Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner. Proc Natl Acad Sci USA 102: 13141–13146.
- , , . 1999. Accelerated wound healing in mice with a disruption of the thrombospondin 2 gene. J Invest Dermatol 113: 782–787.
- , , , , . 2007. Molecular basis for the nerve dependence of limb regeneration in an adult vertebrate. Science 318: 772–777.
- . 2002. Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth. J Cell Mol Med 6: 1–12.Direct Link:
- , , . 1978. Isolation and characterization of a high molecular weight glycoprotein from human blood platelets. J Biol Chem 253: 8609–8616.
- , , . 2010. Skin wound healing in axolotls: a scarless process. J Exp Zool B Mol Dev Evol 314: 684–697.Direct Link:
- , , , . 2001. The chick transcriptional repressor Nkx3.2 acts downstream of Shh to promote BMP-dependent axial chondrogenesis. Dev Cell 1: 411–422.
- , , , . 2003. Extending the table of stages of normal development in the axolotl: limb development. Dev Dyn 226: 555–560.Direct Link:
- , , . 1990. An extracellular matrix molecule of newt and axolotl regenerating limb blastemas and embryonic limb buds: immunological relationship of MT1 antigen with tenascin. Development 108: 657–668.
- , , , , . 1997. Thrombospondin-1 modulates angiogenesis in vitro by up-regulation of matrix metalloproteinase-9 in endothelial cells. Exp Cell Res 235: 403–412.
- , , , , , , , , , , , , . 2009. Proteomic analysis of blastema formation in regenerating axolotl limbs. BMC Biol 7: 83.
- , , . 1987. Thrombospondin in early human wound tissue. J Invest Dermatol 89: 551–554.
- , , , , , . 2005. Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1. Proc Natl Acad Sci USA 102: 13147–13152.
- , , , , , , , . 2001. Analysis of the tendon cell fate using scleraxis, a specific marker for tendons and ligaments. Development 128: 3855–3866.
- , . 1975. Nerves and angiogenesis in amphibian limb regeneration. Nature 257: 224–225.
- , , , , . 2005. Normal newt limb regeneration requires matrix metalloproteinase function. Dev Biol 279: 86–98.
- , , , , . 1999. Expression of Mmp-9 and related matrix metalloproteinase genes during axolotl limb regeneration. Dev Dyn 216: 2–9.Direct Link: