Special Issue Reviews–A Peer Reviewed Forum
“Soft” tissue patterning: Muscles and tendons of the limb take their form
Article first published online: 24 MAR 2011
Copyright © 2011 Wiley-Liss, Inc.
Special Issue: Special Issue on Limb Development
Volume 240, Issue 5, pages 1100–1107, May 2011
How to Cite
Hasson, P. (2011), “Soft” tissue patterning: Muscles and tendons of the limb take their form. Dev. Dyn., 240: 1100–1107. doi: 10.1002/dvdy.22608
- Issue published online: 20 APR 2011
- Article first published online: 24 MAR 2011
- Manuscript Accepted: 22 FEB 2011
- Rappaport Family Institute for Research in the Medical Sciences
- connective tissue
The musculoskeletal system grants our bodies a vast range of movements. Because it is mainly composed of easily identifiable components, it serves as an ideal model to study patterning of the specific tissues that make up the organ. Surprisingly, although critical for the function of the musculoskeletal system, understanding of the embryonic processes that regulate muscle and tendon patterning is very limited. The recent identification of specific markers and the reagents stemming from them has revealed some of the molecular events regulating patterning of these soft tissues. This review will focus on some of the current work, with an emphasis on the roles of the muscle connective tissue, and discuss several key points that addressing them will advance our understanding of these patterning events. Developmental Dynamics 240:1100–1107, 2011. © 2011 Wiley-Liss, Inc.