Special Issue Patterns & Phenotypes
3D expression patterns of cell cycle genes in the developing chick wing and comparison with expression patterns of genes implicated in digit specification
Article first published online: 20 APR 2011
Copyright © 2011 Wiley-Liss, Inc.
Special Issue: Special Issue on Limb Development
Volume 240, Issue 5, pages 1278–1288, May 2011
How to Cite
Welten, M., Pavlovska, G., Chen, Y., Teruoka, Y., Fisher, M., Bangs, F., Towers, M. and Tickle, C. (2011), 3D expression patterns of cell cycle genes in the developing chick wing and comparison with expression patterns of genes implicated in digit specification. Dev. Dyn., 240: 1278–1288. doi: 10.1002/dvdy.22633
- Issue published online: 20 APR 2011
- Article first published online: 20 APR 2011
- Manuscript Accepted: 2 MAR 2011
- BBSRC. Grant Number: BB/G00093X/1
- MRC. Grant Number: G9806660 and G0801092
- The Royal Society
Additional Supporting Information may be found in the online version of this article.
|DVDY_22633_sm_SuppFig1.tif||1623K||Supporting Information Figure 1. Flow chart of the 50 genes indicating which genes have previously been studied and the new genes added in this study.|
|DVDY_22633_sm_SuppFig2.tif||3272K||Supporting Information Figure 2. Hierarchical clustering of median 3D expression patterns of cell cycle genes. A: Remaining four spatial domain clusters s (which did not contain high level PCNA expression): clusters 10, 11, 14, and 17. B: Composite visualization of all the spatial domains of the cell cycle genes at stage 24; dorsal view (top) and ventral view (bottom).|
|DVDY_22633_sm_SuppFig3.tif||1977K||Supporting Information Figure 3. Movie showing the spatial domain clusters for the cell cycle genes in stage-24 chick wing. Spatial domain cluster 18 and then 19 appear first, then domain clusters 13 and 15.|
|DVDY_22633_sm_SuppMovie1.mpg||3016K||Supporting Information Movie 1. 3D expression patterns of (i) Angpt, (ii) Bmp2, (iii) Hoxa9, (iv) Hoxd11, (v) Hoxd12, (vi) Notum (vii) Ptch1, (viii) Snai2, (ix) Wnt5a. Virtual sections taken through different planes of reference wing bud to show levels of expression. A: Reference wing buds showing the planes of section (orange bars) to give views shown in B (A-Po/Pr-Di), C ( A-Po/Do-V), and D (V-Do/Pr-Di). B–D: Heat map images of median expression patterns. Heat map scale bar bottom right. A, Anterior; Po, Posterior; Pr, Proximal; Di, Distal; Do, Dorsal; V, Ventral.|
|DVDY_22633_sm_SuppMovie2.mpg||2370K||Supporting Information Movie 2. Movie showing the spatial domain clusters for the total data set (50 genes). Spatial domain cluster 24 and 24a appear first, then domain clusters 15, 16, 21.|
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