A focal adhesion protein-based mechanochemical checkpoint regulates cleft progression during branching morphogenesis
Article first published online: 19 OCT 2011
Copyright © 2011 Wiley Periodicals, Inc.
Volume 240, Issue 11, page spcone, November 2011
How to Cite
Daley, W. P., Kohn, J. M. and Larsen, M. (2011), A focal adhesion protein-based mechanochemical checkpoint regulates cleft progression during branching morphogenesis. Dev. Dyn., 240: spcone. doi: 10.1002/dvdy.22767
- Issue published online: 19 OCT 2011
- Article first published online: 19 OCT 2011
- Manuscript Accepted: 15 JUL 2011
- NIH. Grant Numbers: R01 DE019244, R21DE019197, DE020402
- The University at Albany
- Cited By
- branching morphogenesis;
- focal adhesions;
- integrin activation
E13 mouse submandibular salivary gland (SMG) cultured for 24 hours ex vivo and immunostained for collagen IV (blue) to mark the basement membrane, Na+/K+ ATPase (green) which is preferential for the epithelium, and the focal adhesion protein vinculin (red) to delineate cell-matrix adhesions. Note that vinculin localizes the most strongly to regions of cell-matrix contact immediately adjacent to the basement membrane. From Daley et al., Developmental Dynamics 240:2069–2083, 2011.