Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development
Article first published online: 25 JAN 2012
Copyright © 2012 Wiley Periodicals, Inc.
Volume 241, Issue 3, pages 493–504, March 2012
How to Cite
Le, T. T., Conley, K. W., Mead, T. J., Rowan, S., Yutzey, K. E. and Brown, N. L. (2012), Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development. Dev. Dyn., 241: 493–504. doi: 10.1002/dvdy.23739
- Issue published online: 14 FEB 2012
- Article first published online: 25 JAN 2012
- Accepted manuscript online: 13 JAN 2012 09:39AM EST
- Manuscript Accepted: 3 JAN 2012
- NIH. Grant Numbers: EY18097, HL094319
- AHA. Grant Number: 09PRE2060551
Additional supporting information may be found in the online version of this article.
|DVDY_23739_sm_SuppFig1.tif||4010K||Supporting Information Figre 1. Ap2αCre expression in the neural crest and ectodermal cell lineages. Ap2αCre;Rosa26R mice were assayed for β-Galactosidase activity (blue staining). A: Expression was detected in neural crest-derived structures including the cranial neural crest, within jaw and frontonasal processes, the cardiac neural crest in the outflow tract, and the trunk neural crest, as denoted by expression in the dorsal root ganglia (black arrows). β-Galactosidase expression was also present in the lens and limbs (white arrows), where AP2α protein or mRNA expression have been previously reported (Zhang et al., 1996; West-Mays et al., 1999; Macatee et al., 2003). B: embryonic day (E) 14.5 Ap2αCre;Rosa26R embryos also have Cre-mediated activation of lacZ reporter expression in the cardiac outflow tract (OFT, black arrow). Rostral is left in A, anterior is up in B. A = ×10, B = ×50 magnification.|
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