Additional Supporting Information may be found in the online version of this article.

DVDY_23758_sm_SuppMovieS1.mov4642KSupporting Information Movie S1. This movie shows the embryonic development of an embryo at approximately 20°C; the A-quadrant of an egg at 16-cell stage is in the centre. Overlay of original imaging data and SimiBioCell analysis with highlighted cells which are involved in sickle-shape formation (color code: A: yellow spheres; a: yellow stars; B: green spheres, b: green cubes; D: red spheres, d: red cubes). The movie starts at 16-cell stage and ends with the sickle-shaped cell formation (indicated with a black dashed line at the end of the movie). Duration is 14 hours of development and time interval between each frame is 2 min.

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