• Agarwal P, Wylie JN, Galceran J, Arkhitko O, Li C, Deng C, Grosschedl R, Bruneau BG. 2003. Tbx5 is essential for forelimb bud initiation following patterning of the limb field in the mouse embryo. Development 130: 623633.
  • Birling MC, Gofflot F, Warot X. 2009. Site-specific recombinases for manipulation of the mouse genome. Methods Mol Biol 561: 245263.
  • Burke AC, Nelson CE, Morgan BA, Tabin C. 1995. Hox genes and the evolution of vertebrate axial morphology. Development 121: 333346.
  • Capdevila J, Izpisua Belmonte JC. 2001. Patterning mechanisms controlling vertebrate limb development. Annu Rev Cell Dev Biol 17: 87132.
  • Chapman DL, Garvey N, Hancock S, Alexiou M, Agulnik SI, Gibson-Brown JJ, Cebra-Thomas J, Bollag RJ, Silver LM, Papaioannou VE. 1996. Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development. Dev Dyn 206: 379390.
  • Cohen B, McGuffin ME, Pfeifle C, Segal D, Cohen SM. 1992. apterous, a gene required for imaginal disc development in Drosophila encodes a member of the LIM family of developmental regulatory proteins. Genes Dev 6: 715729.
  • Crossley PH, Minowada G, MacArthur CA, Martin GR. 1996. Roles for FGF8 in the induction, initiation, and maintenance of chick limb development. Cell 84: 127136.
  • Diaz-Benjumea FJ, Cohen SM. 1993. Interaction between dorsal and ventral cells in the imaginal disc directs wing development in Drosophila. Cell 75: 741752.
  • Gibson-Brown JJ, Agulnik SI, Chapman DL, Alexiou M, Garvey N, Silver LM, Papaioannou VE. 1996. Evidence of a role for T-box genes in the evolution of limb morphogenesis and the specification of forelimb/hindlimb identity. Mech Dev 56: 93101.
  • Kawakami Y, Marti M, Kawakami H, Itou J, Quach T, Johnson A, Sahara S, O'Leary DD, Nakagawa Y, Lewandoski M, Pfaff S, Evans SM, Izpisua Belmonte JC. 2011. Islet1-mediated activation of the {beta}-catenin pathway is necessary for hindlimb initiation in mice. Development 138: 44654473.
  • Lewandoski M, Sun X, Martin GR. 2000. Fgf8 signalling from the AER is essential for normal limb development. Nat Genet 26: 460463.
  • Min H, Danilenko DM, Scully SA, Bolon B, Ring BD, Tarpley JE, DeRose M, Simonet WS. 1998. Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless. Genes Dev 12: 31563161.
  • Moon AM, Capecchi MR. 2000. Fgf8 is required for outgrowth and patterning of the limbs. Nat Genet 26: 455459.
  • Mukhopadhyay M, Teufel A, Yamashita T, Agulnick AD, Chen L, Downs KM, Schindler A, Grinberg A, Huang SP, Dorward D, Westphal H. 2003. Functional ablation of the mouse Ldb1 gene results in severe patterning defects during gastrulation. Development 130: 495505.
  • Naiche LA, Papaioannou VE. 2003. Loss of Tbx4 blocks hindlimb development and affects vascularization and fusion of the allantois. Development 130: 26812693.
  • Ng M, Diaz-Benjumea FJ, Vincent JP, Wu J, Cohen SM. 1996. Specification of the wing by localized expression of wingless protein. Nature 381: 316318.
  • Ohuchi H, Nakagawa T, Yamamoto A, Araga A, Ohata T, Ishimaru Y, Yoshioka H, Kuwana T, Nohno T, Yamasaki M, Itoh N, Noji S. 1997. The mesenchymal factor, FGF10, initiates and maintains the outgrowth of the chick limb bud through interaction with FGF8, an apical ectodermal factor. Development 124: 22352244.
  • Perantoni AO, Timofeeva O, Naillat F, Richman C, Pajni-Underwood S, Wilson C, Vainio S, Dove LF, Lewandoski M. 2005. Inactivation of FGF8 in early mesoderm reveals an essential role in kidney development. Development 132: 38593871.
  • Sekine K, Ohuchi H, Fujiwara M, Yamasaki M, Yoshizawa T, Sato T, Yagishita N, Matsui D, Koga Y, Itoh N, Kato S. 1999. Fgf10 is essential for limb and lung formation. Nat Genet 21: 138141.
  • Sun X, Mariani FV, Martin GR. 2002. Functions of FGF signalling from the apical ectodermal ridge in limb development. Nature 418: 501508.
  • Sun Y, Liang X, Najafi N, Cass M, Lin L, Cai CL, Chen J, Evans SM. 2007. Islet 1 is expressed in distinct cardiovascular lineages, including pacemaker and coronary vascular cells. Dev Biol 304: 286296.
  • Tzchori I, Day TF, Carolan PJ, Zhao Y, Wassif CA, Li L, Lewandoski M, Gorivodsky M, Love PE, Porter FD, Westphal H, Yang Y. 2009. LIM homeobox transcription factors integrate signaling events that control three-dimensional limb patterning and growth. Development 136: 13751385.
  • Verheyden JM, Lewandoski M, Deng C, Harfe BD, Sun X. 2005. Conditional inactivation of Fgfr1 in mouse defines its role in limb bud establishment, outgrowth and digit patterning. Development 132: 42354245.
  • Vogel A, Rodriguez C, Izpisua-Belmonte JC. 1996. Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb. Development 122: 17371750.
  • Vooijs M, Jonkers J, Berns A. 2001. A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent. EMBO Rep 2: 292297.
  • Zeller R, Lopez-Rios J, Zuniga A. 2009. Vertebrate limb bud development: moving towards integrative analysis of organogenesis. Nat Rev Genet 10: 845858.
  • Zhao Y, Kwan KM, Mailloux CM, Lee WK, Grinberg A, Wurst W, Behringer RR, Westphal H. 2007. LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum. Proc Natl Acad Sci USA 104: 1318213186.