Neural crest cells pattern the surface cephalic ectoderm during FEZ formation
Article first published online: 12 MAR 2012
Copyright © 2012 Wiley Periodicals, Inc.
Volume 241, Issue 4, pages 732–740, April 2012
How to Cite
Hu, D. and Marcucio, R. S. (2012), Neural crest cells pattern the surface cephalic ectoderm during FEZ formation. Dev. Dyn., 241: 732–740. doi: 10.1002/dvdy.23764
- Issue published online: 12 MAR 2012
- Article first published online: 12 MAR 2012
- Accepted manuscript online: 22 FEB 2012 12:00AM EST
- Manuscript Accepted: 13 FEB 2012
- NIH. Grant Number: NIDCR: R01-DE018234; R01-DE019638
Additional Supporting Information is available in the online version of this article.
|DVDY_23764_sm_suppFig1.tif||774K||Supporting Information Figure 1. Location of bead placement at HH 11. Ion exchange beads were soaked in concentrations of SU5402 10 mM/ml dissolved in dimethylsulfoxide (DMSO) or beads were soaked in DMSO alone as the control for 1 hr at RT and then placed into the forebrain after emigration of neural crest cells was complete. The bead is labeled and outlined with a dotted white line. The embryo is outlined with a solid black line. The midbrain (M) and hindbrain (H) are labeled. Scale bar = 500 μm.|
|DVDY_23764_sm_suppFig2.tif||297K||Supporting Information Figure 2. SU5402 creates vascular defects in the head of treated embryos. A: Blood flow in a control embryo illustrates complete perfusion of the head (arrows; n = 5). B: After blockade of FGF signaling, blood flow to the head is absent (n = 8). The avascular region of the developing head is outlined with a dotted line. Scale bar = 1 mm.|
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