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Keywords:

  • Tol2 gene trap;
  • endothelial cells;
  • vein;
  • vasculature;
  • central nervous system

Abstract

COVER PHOTOGRAPH: Confocal image of live 36 hpf double transgenic appais22Gt; Tg(flk1:moesin-gfp)is1 embryo. The image shows accumulation of appaRFP fusion proteins specifically at the veinous vessels in the head and anterior region of the trunk, including the midcerebral and common cardinal veins. Arteries and veins are visualized by expression of moesin:GFP throughout all endothelial cells of the vasculature. From Liao et al., Developmental Dynamics 241:415–425, 2012.