Drs. Liao and Wang contributed equally to this work.
Tol2 gene trap integrations in the zebrafish amyloid precursor protein genes appa and aplp2 reveal accumulation of secreted APP at the embryonic veins
Article first published online: 17 JUL 2012
Copyright © 2012 Wiley Periodicals, Inc.
Volume 241, Issue 8, August 2012
How to Cite
Liao, H.-K., Wang, Y., Noack Watt, K. E., Wen, Q., Breitbach, J., Kemmet, C. K., Clark, K. J., Ekker, S. C., Essner, J. J. and McGrail, M. (2012), Tol2 gene trap integrations in the zebrafish amyloid precursor protein genes appa and aplp2 reveal accumulation of secreted APP at the embryonic veins. Dev. Dyn., 241: n/a. doi: 10.1002/dvdy.23829
- Issue published online: 17 JUL 2012
- Article first published online: 17 JUL 2012
- Center for Integrated Animal Genomics, ISU
- Roy J. Carver Charitable trust. Grant Number: 07-2991
- NIH-NCCR. Grant Number: P40 RR012546 to ZIRC
- NIH. Grant Number: DA14546
- Cited By
- Tol2 gene trap;
- endothelial cells;
- central nervous system
COVER PHOTOGRAPH: Confocal image of live 36 hpf double transgenic appais22Gt; Tg(flk1:moesin-gfp)is1 embryo. The image shows accumulation of appaRFP fusion proteins specifically at the veinous vessels in the head and anterior region of the trunk, including the midcerebral and common cardinal veins. Arteries and veins are visualized by expression of moesin:GFP throughout all endothelial cells of the vasculature. From Liao et al., Developmental Dynamics 241:415–425, 2012.