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REFERENCES

  • Abramoff MD, Magalhaes PJ, Ram SJ. 2004. Image Processing with ImageJ. Biophotonics Int 11: 3642.
  • Acampora D, Merlo GR, Paleari L, Zerega B, Pia Postiglione M, Mantero S, Bober E, Barbieri O, Simeone A, Levi G. 1999. Craniofacial, vestibular and bone defects in mice lacking the Distal-less related gene Dlx5. Development 126: 37953809.
  • Alappat SR, Zhang Z, Suzuki K, Zhang X, Liu H, Jiang R, Yamada G, Chen Y. 2005. The cellular and molecular etiology of the cleft secondary palate in Fgf10 mutant mice. Dev Biol 277: 102113.
  • Anderson S, Eisenstat D, Shi L, Rubenstein JL. 1997. Interneuron migration from basal forebrain to neocortex: dependence on Dlx genes. Science 278: 474476
  • Beverdam A, Merlo, GR, Paleari L, Mantero S, Genova F, Barbieri O, Janvier P, Levi G. 2002. Jaw transformation with gain of symmetry after Dlx5/Dlx6 inactivation: mirror of the past? Genesis 34: 221227.
  • Bulfone A, Kim HJ, Puelles L, Porteus MH, Grippo JF, Rubenstein JL. 1993. The mouse Dlx-2 (Tes-1) gene is expressed in spatially restricted domains of the forebrain, face and limbs in midgestation mouse embryos. Mech Dev 40: 129140.
  • Bush JO, Jiang R. 2012. Palatogenesis: morphogenetic and molecular mechanisms of secondary palate development. Development 139: 231243.
  • Chai Y, Jiang X, Ito Y, Bringas JrP, Han J, Rowitch DH, Soriano P, McMahon AP, Sucov HM. 2000. Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis. Development 127: 16711679.
  • Choi GB, Dong HW, Murphy AJ, Valenzuela DM, Yancopoulos GD, Swanson LW, Anderson DJ. 2005. Lhx6 delineates a pathway mediating innate reproductive behaviors from the amygdala to the hypothalamus. Neuron 46: 647660.
  • Colvin JS, Feldman B, Nadeau JH, Goldfarbm M, Ornitz DM. 1999. Genomic organization and embryonic expression of the mouse fibroblast growth factor 9 gene. Dev Dyn 216: 7288.
  • Dahmane N, Charron G, Lopes C, Yaspo ML, Maunoury C, Decorte L, Sinet PM, Bloch B, Delabar JM 1995. Down syndrome-critical region contains a gene homologous to Drosophila sim expressed during rat and human central nervous system development. Proc Natl Acad Sci USA 92: 91919195.
  • Danielian PS, Muccino D, Rowitch DH, Michael SK, McMahon AP. 1998. Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. Curr Biol 8: 13231326.
  • Denaxa M, Sharpe PT, Pachnis V. 2009. The LIM homeodomain transcription factors Lhx6 and Lhx7 are key regulators of mammalian dentition. Dev Biol 333: 324336.
  • Depew MJ, Liu JK, Long JE, Presley R, Meneses JJ, Pedersen RA, Rubenstein JLR. 1999. Dlx5 regulates regional development of the branchial arches and sensory capsules. Development 126: 8313846.
  • Depew MJ, Lufkin T, Rubenstein JLR. 2002. Specification of jaw subdivisions by Dlx genes. Science 298: 381385.
  • Dixon MJ, Marazita ML, Beaty TH, Murray JC. 2011. Cleft lip and palate: understanding genetic and environmental influences. Nat Rev Genet 12: 167178.
  • Dollé P, Price M, Duboule D. 1992. Expression of the murine Dlx-1 homeobox gene during facial, ocular and limb development. Differentiation 49: 9399.
  • Dudas M, Kim J, Li W-Y, Nagy A, Larsson J, Karlsson S, Chai Y, Kaartinen V. 2006. Epithelial and ectomesenchymal role of the type I TGF-β receptor ALK5 during facial morphogenesis and palatal fusion. Dev Biol 296: 298314.
  • Fan CM, Kuwana E, Bulfone A, Fletcher CF, Copeland NG, Jenkins NA, Crews S, Martinez S, Puelles L, Rubenstein JL, Tessier-Lavigne M. 1996. Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome. Mol Cell Neurosci 7: 116.
  • Ferguson MW. 1988. Palate development. Development 103( Suppl): 4160.
  • Grieshammer U, Cebrián C, Ilagan R, Meyers E, Herzlinger D, Martin GR. 2005. FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons. Development 132: 38473857.
  • Grigoriou M, Tucker AS, Sharpe PT, Pachnis V. 1998. Expression and regulation of Lhx6 and Lhx7, a novel subfamily of LIM homeodomain encoding genes, suggests a role in mammalian head development. Development 125: 20632074.
  • Gritli-Linde A. 2007. Molecular control of secondary palate development. Dev Biol 301: 309326
  • Gritli-Linde A. 2008. The etiopathogenesis of cleft lip and cleft palate: usefulness and caveats of mouse models. Curr Top Dev Biol 84: 37138.
  • Han J, Mayo J, Xu X, Li J, Bringas JrP, Maas RL, Rubenstein JLR, Chai Y. 2009. Indirect modulation of Shh signaling by Dlx5 affects the oral-nasal patterning of palate and rescues cleft palate in Msx1-null mice. Development 136: 42254233.
  • Hilliard SA, Yu L, Gu S, Zhang Z, Chen YP. 2005. Regional regulation of palatal growth and patterning along the anterior-posterior axis in mice. J Anat 207: 655667.
  • Ito Y, Yeo JY, Chytil A, Han J, Bringas JrP, Nakajima A, Shuler CF, Moses HL, Chai Y. 2003. Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects. Development 130: 52695280.
  • Iwata J, Tung L, Urata M, Hacia JG, Pelikan R, Suzuki A, Ramenzoni L, Chaudhry O, Parada C, Sanchez-Lara P, Chai Y. 2012. Fibroblast growth factor 9 (Fgf9)-Pituitary homeobox 2 (Pitx2) pathway mediates transforming growth factor β (Tgfβ) signaling to regulate cell proliferation in palatal mesenchyme during mouse palatogenesis. J Biol Chem 287: 23532363.
  • Jeong J, Mao J, Tenzen T, Kottmann AH, McMahon AP. 2004. Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia. Genes Dev 18: 937951.
  • Jeong J, Li X, McEvilly R, Rosenfeld MG, Lufkin T, Rubenstein JLR. 2008. Dlx genes pattern mammalian jaw primordium by regulating both lower jaw-specific and upper jaw-specific genetic programs. Development 135: 29052916.
  • Kettunen P, Thesleff I. 1998. Expression and function of FGFs-4, -8, and -9 suggest functional redundancy and repetitive use as epithelial signals during tooth morphogenesis. Dev Dyn 211: 256268.
  • Kim BM, Miletich I, Mao J, McMahon AP, Sharpe PA, Shivdasani RA. 2007. Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen. Development 134: 36033613.
  • Ko SO, Chung IH, Xu X, Oka S, Zhao H, Cho ES, Deng C, Chai Y. 2007. Smad4 is required to regulate the fate of cranial neural crest cells. Dev Biol 312: 435447.
  • Lan Y, Jiang R. 2009. Sonic hedgehog signaling regulates reciprocal epithelial-mesenchymal interactions controlling palatal outgrowth. Development 136: 13871396.
  • Lan Y, Ovitt CE, Cho ES, Maltby KM, Wang Q, Jiang R. 2004. Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis. Development 131: 32073216.
  • McKeown SJ, Newgreen DF, Farlie PG. 2005. Dlx2 over-expression regulates cell adhesion and mesenchymal condensation in ectomesenchyme. Dev Biol 281: 2237.
  • Merlo GR, Paleari L, Mantero S, Zerega, B, Adamska M, Rinkwitz S, Bober E, Levi G. 2002. The Dlx5 homeobox gene is essential for vestibular morphogenesis in the mouse embryo through a BMP4-mediated pathway. Dev Biol 248: 157169.
  • Miletich I, Yu WY, Zhang R, Yang K, Caixeta de Andrade S, Pereira SF, Ohazama A, Mock OB, Buchner G, Sealby J, Webster Z, Zhao M, Bei M, Sharpe PT. 2011. Developmental stalling and organ-autonomous regulation of morphogenesis. Proc Natl Acad Sci USA 108: 1927019275.
  • Mitchell PJ, Timmons PM, Hebert JM, Rigby PWJ, Tjian R. 1991. Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis. Genes dev 5: 105119.
  • Panganiban G, Rubenstein JLR. 2002. Developmental functions of the Distal-less/Dlx homeobox genes. Development 129: 43714836.
  • Porteus MH, Bulfone A, Ciaranello RD, Rubenstein JLR. 1991. Isolation and characterization of a novel cDNA clone encoding a homeodomain that is developmentally regulated in the ventral forebrain. Neuron 77: 221229.
  • Price M, Lemaistre M, Pischetola M, di Lauro R, Duboule D. 1991. A mouse gene related to Distal-less shows a restricted expression in the developing forebrain. Nature 351: 748751.
  • Qiu M, Bulfone A, Martinez S, Meneses J, Shimamura K, Pedersen RA, Rubenstein JLR. 1995. Null mutation of Dlx-2 results in abnormal morphogenesis of proximal first and second branchial arch derivatives and abnormal differentiation in the forebrain. Genes Dev 9: 25232538.
  • Qiu M, Bulfone A, Ghattas I, Meneses JJ, Christensen L, Sharpe PT, Presley R, Pederson RA, Rubenstein JLR. 1997. Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. Dev Biol 185: 165184.
  • Rice R, Spencer-Dene B, Connor EC, Gritli-Linde A, McMahon AP, Dickson C, Thesleff I, Rice DP. 2004. Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate. J Clin Invest 113: 16921700.
  • Robinson GW, Mahon KA. 1994. Differential and overlapping expression domains of Dlx-2 and Dlx-3 suggest distinct roles for Distal-less homeobox genes in craniofacial development. Mech Dev 48: 199215.
  • Robledo RF, Lufkin T. 2006. Dlx5 and Dlx6 homeobox genes are required for specification of the mammalian vestibular apparatus. Genesis 44: 425437.
  • Robledo RF, Rajan L, Li X, Lufkin T. 2002. The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development. Genes Dev 16: 10891101.
  • Shamblott MJ, Bugg EM, Lawler AM, Gearhart JD 2002. Craniofacial abnormalities resulting from targeted disruption of the murine Sim2 gene. Dev Dyn 224: 373380.
  • Simeone A, Acampora D, Pannese M, D'Esposito M, Stornaiuolo A, Gulisano M, Mallamaci A, Kastury K, Druck T, Huebner K, Boncinelli E. 1994. Cloning and characterization of two members of the vertebrate Dlx gene family. Proc Natl Acad Sci USA 91: 22502254.
  • So PL, Danielian PS. 1999. Cloning and expression analysis of a mouse gene related to Drosophila odd-skipped. Mech Dev 84: 157160.
  • Soriano P. 1999. Generalized LacZ expression with the ROSA26 Cre reporter strain. Nat Genet 21: 7071.
  • Sperber SM, Saxena V, Hatch G, Ekker M. 2008. Zebrafish dlx2a contributes to hindbrain neural crest survival, is necessary for differentiation of sensory ganglia and functions with dlx1a in maturation of the arch cartilage elements. Dev Biol 314: 5970.
  • Thomas BL, Tucker AS, Qui M, Ferguson, CA, Hardcastle Z, Rubenstein JL, Sharpe PT. 1997. Role of Dlx-1 and Dlx-2 genes in patterning of the murine dentition. Development 124: 48114818.
  • Tissier-Seta JP, Mucchielli ML, Mark M, Mattei MG, Goridis C, Brunet JF. 1995. Barx1, a new mouse homeodomain transcription factor expressed in cranio-facial ectomesenchyme and the stomach. Mech Dev 51: 315.
  • Tolarova MM, Cervenka J. 1998. Classification and birth prevalence of orofacial clefts. Am J Med Genet 75: 126137.
  • Yu K, Ornitz DM. 2011. Histomorphological study of palatal shelf elevation during murine secondary palate formation. Dev Dyn 240: 17371744.
  • Zhang Z, Song Y, Zhao X, Zhang X, Fermin C, Chen Y. 2002. Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a network of BMP and Shh signaling in the regulation of mammalian palatogenesis. Development 129: 41354146.
  • Zhao Y, Guo YJ, Tomac AC, Taylor NR, Grinberg A, Lee EJ, Huang S, Westphal H. 1999. Isolated cleft palate in mice with a targeted mutation of the LIM homeobox gene lhx8. Proc Natl Acad Sci USA 96: 1500215006.