Normalized shape and location of perturbed craniofacial structures in the Xenopus tadpole reveal an innate ability to achieve correct morphology

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Abstract

COVER PHOTOGRAPH: Visualization of the developing neural tube and craniofacial structures using pH and membrane voltage reporter dyes in Xenopus laevis embryos. Manipulation of pH and membrane voltage via misexpression of subunit c of the H+-V-ATPase produces craniofacial abnormalities that are capable of normalizing themselves as the animal develops and ages. From Vandenberg et al., Developmental Dynamics 241:863–878, 2012.

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