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  • Abu-Issa R, Smyth G, Smoak I, Yamamura K, Meyers EN. 2002. Fgf8 is required for pharyngeal arch and cardiovascular development in the mouse. Development 129:46134625.
  • Ai D, Liu W, Ma L, Dong F, Lu MF, Wang D, Verzi MP, Cai C, Gage PJ, Evans S, Black BL, Brown NA, Martin JF. 2006. Pitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardium. Dev Biol 296:437449.
  • Amendt BA, Sutherland LB, Semina EV, Russo AF. 1998. The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities. J Biol Chem 273:2006620072.
  • Arima Y, Miyagawa-Tomita S, Maeda K, Asai R, Seya D, Minoux M, Rijli FM, Nishiyama K, Kim KS, Uchijima Y, Ogawa H, Kurihara Y, Kurihara H. 2012. Preotic neural crest cells contribute to coronary artery smooth muscle involving endothelin signalling. Nat Commun 3:1267.
  • Brown CB, Boyer AS, Runyan RB, Barnett JV. 1996. Antibodies to the Type II TGFbeta receptor block cell activation and migration during atrioventricular cushion transformation in the heart. Dev Biol 174:248257.
  • Buckingham M, Meilhac S, Zaffran S. 2005. Building the mammalian heart from two sources of myocardial cells. Nat Rev Genet 6:826835.
  • Cai CL, Liang X, Shi Y, Chu PH, Pfaff SL, Chen J, Evans S. 2003. Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. Dev Cell 5:877889.
  • Campbell AL, Eng D, Gross MK, Kioussi C. 2012. Prediction of gene network models in limb muscle precursors. Gene 509:1623.
  • Campione M, Ros MA, Icardo JM, Piedra E, Christoffels VM, Schweickert A, Blum M, Franco D, Moorman AF. 2001. Pitx2 expression defines a left cardiac lineage of cells: evidence for atrial and ventricular molecular isomerism in the iv/iv mice. Dev Biol 231:252264.
  • Dodou E, Verzi MP, Anderson JP, Xu SM, Black BL. 2004. Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development. Development 131:39313942.
  • Echelard Y, Vassileva G, McMahon AP. 1994. Cis-acting regulatory sequences governing Wnt-1 expression in the developing mouse CNS. Development 120:22132224.
  • Eng D, Campbell A, Hilton T, Leid M, Gross MK, Kioussi C. 2010. Prediction of regulatory networks in mouse abdominal wall. Gene 469:18.
  • Eng D, Ma HY, Xu J, Shih HP, Gross MK, Kiouss C. 2012. Loss of abdominal muscle in Pitx2 mutants associated with altered axial specification of lateral plate mesoderm. PLoS One 7:e42228.
  • Engleka KA, Manderfield LJ, Brust RD, Li L, Cohen A, Dymecki SM, Epstein JA. 2012. Islet1 derivatives in the heart are of both neural crest and second heart field origin. Circ Res 110:922926.
  • Franco D, Campione M. 2003. The role of Pitx2 during cardiac development. Linking left-right signaling and congenital heart diseases. Trends Cardiovasc Med 13:157163.
  • Frank DU, Fotheringham LK, Brewer JA, Muglia LJ, Tristani-Firouzi M, Capecchi MR, Moon AM. 2002. An Fgf8 mouse mutant phenocopies human 22q11 deletion syndrome. Development 129:45914603.
  • Gage PJ, Suh H, Camper SA. 1999. Dosage requirement of Pitx2 for development of multiple organs. Development 126:46434651.
  • Gage PJ, Rhoades W, Prucka SK, Hjalt T. 2005. Fate maps of neural crest and mesoderm in the mammalian eye. Invest Ophthalmol Vis Sci 46:42004208.
  • Galli D, Dominguez JN, Zaffran S, Munk A, Brown NA, Buckingham ME. 2008. Atrial myocardium derives from the posterior region of the second heart field, which acquires left-right identity as Pitx2c is expressed. Development 135:11571167.
  • Ganga M, Espinoza HM, Cox CJ, Morton L, Hjalt TA, Lee Y, Amendt BA. 2003. PITX2 isoform-specific regulation of atrial natriuretic factor expression: synergism and repression with Nkx2.5. J Biol Chem 278:2243722445.
  • Hamblet NS, Lijam N, Ruiz-Lozano P, Wang J, Yang Y, Luo Z, Mei L, Chien KR, Sussman DJ, Wynshaw-Boris A. 2002. Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure. Development 129:58275838.
  • Harel IMY, Avraham R, Rinon A, Ma HY, Cross J.W, Leviatan N, Hegesh JT, Roy A, Jacob-Hirsch J, Rechavi G, Carvajal J, Tole S, Kioussi C, Quaggin S, Tzahor E. 2012. Pharyngeal mesoderm regulatory network controls cardiac and head muscle morphogenesis. Proc Natl Acad Sci USA (in press).
  • Harvey RP. 2002. Patterning the vertebrate heart. Nat Rev Genet 3:544556.
  • Hilton T, Gross MK, Kioussi C. 2010. Pitx2-dependent occupancy by histone deacetylases is associated with T-box gene regulation in mammalian abdominal tissue. J Biol Chem 285:1112911142.
  • Hoffman JI, Kaplan S. 2002. The incidence of congenital heart disease. J Am Coll Cardiol 39:18901900.
  • Hu T, Yamagishi H, Maeda J, McAnally J, Yamagishi C, Srivastava D. 2004. Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors. Development 131:54915502.
  • Hurlstone AF, Haramis AP, Wienholds E, Begthel H, Korving J, Van Eeden F, Cuppen E, Zivkovic D, Plasterk RH, Clevers H. 2003. The Wnt/beta-catenin pathway regulates cardiac valve formation. Nature 425:633637.
  • Ilagan R, Abu-Issa R, Brown D, Yang YP, Jiao K, Schwartz RJ, Klingensmith J, Meyers EN. 2006. Fgf8 is required for anterior heart field development. Development 133:24352445.
  • Joyner A, Wall N. 2008. Immunohistochemistry of whole-mount mouse embryos. CSH Protoc 2008:pdb prot4820.
  • Kelly RG, Papaioannou VE. 2007. Visualization of outflow tract development in the absence of Tbx1 using an FgF10 enhancer trap transgene. Dev Dyn 236:821828.
  • Kelly RG, Brown NA, Buckingham ME. 2001. The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm. Dev Cell 1:435440.
  • Kioussi C, Briata P, Baek SH, Rose DW, Hamblet NS, Herman T, Ohgi KA, Lin C, Gleiberman A, Wang J, Brault V, Ruiz-Lozano P, Nguyen HD, Kemler R, Glass CK, Wynshaw-Boris A, Rosenfeld MG. 2002. Identification of a Wnt/Dvl/beta-Catenin [RIGHTWARDS ARROW] Pitx2 pathway mediating cell-type-specific proliferation during development. Cell 111:673685.
  • Kirby M. 2007. Cardiac development. New York: Oxford University Press.
  • Kitamura K, Miura H, Miyagawa-Tomita S, Yanazawa M, Katoh-Fukui Y, Suzuki R, Ohuchi H, Suehiro A, Motegi Y, Nakahara Y, Kondo S, Yokoyama M. 1999. Mouse Pitx2 deficiency leads to anomalies of the ventral body wall, heart, extra- and periocular mesoderm and right pulmonary isomerism. Development 126:57495758.
  • Kyrylkova K, Kyryachenko S, Kioussi C, Leid M. 2012. Determination of gene expression patterns by in situ hybridization in sections. Methods Mol Biol 887:2331.
  • Lin CR, Kioussi C, O'Connell S, Briata P, Szeto D, Liu F, Izpisua-Belmonte JC, Rosenfeld MG. 1999. Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis. Nature 401:279282.
  • Lin Q, Schwarz J, Bucana C, Olson EN. 1997. Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C. Science 276:14041407.
  • Liu C, Liu W, Palie J, Lu MF, Brown NA, Martin JF. 2002. Pitx2c patterns anterior myocardium and aortic arch vessels and is required for local cell movement into atrioventricular cushions. Development 129:50815091.
  • Liu W, Selever J, Lu MF, Martin JF. 2003. Genetic dissection of Pitx2 in craniofacial development uncovers new functions in branchial arch morphogenesis, late aspects of tooth morphogenesis and cell migration. Development 130:63756385.
  • Liu W, Selever J, Wang D, Lu MF, Moses KA, Schwartz RJ, Martin JF. 2004. Bmp4 signaling is required for outflow-tract septation and branchial-arch artery remodeling. Proc Natl Acad Sci USA 101:44894494.
  • Lozano-Velasco E, Chinchilla A, Martinez-Fernandez S, Hernandez-Torres F, Navarro F, Lyons GE, Franco D, Aranega AE. 2011. Pitx2c modulates cardiac-specific transcription factors networks in differentiating cardiomyocytes from murine embryonic stem cells. Cells Tissues Organs 194:349362.
  • Lu MF, Pressman C, Dyer R, Johnson RL, Martin JF. 1999. Function of Rieger syndrome gene in left-right asymmetry and craniofacial development. Nature 401:276278.
  • Lyons KM, Pelton RW, Hogan BL. 1990. Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A). Development 109:833844.
  • Ma L, Lu MF, Schwartz RJ, Martin JF. 2005. Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning. Development 132:56015611.
  • Mao X, Fujiwara Y, Chapdelaine A, Yang H, Orkin SH. 2001. Activation of EGFP expression by Cre-mediated excision in a new ROSA26 reporter mouse strain. Blood 97:324326.
  • McCulley DJ, Kang JO, Martin JF, Black BL. 2008. BMP4 is required in the anterior heart field and its derivatives for endocardial cushion remodeling, outflow tract septation, and semilunar valve development. Dev Dyn 237:32003209.
  • Monzen K, Shiojima I, Hiroi Y, Kudoh S, Oka T, Takimoto E, Hayashi D, Hosoda T, Habara-Ohkubo A, Nakaoka T, Fujita T, Yazaki Y, Komuro I. 1999. Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4. Mol Cell Biol 19:70967105.
  • Niessen K, Karsan A. 2008. Notch signaling in cardiac development. Circ Res 102:11691181.
  • Nowotschin S, Liao J, Gage PJ, Epstein JA, Campione M, Morrow BE. 2006. Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field. Development 133:15651573.
  • Oliver G, Wehr R, Jenkins NA, Copeland NG, Cheyette BN, Hartenstein V, Zipursky SL, Gruss P. 1995. Homeobox genes and connective tissue patterning. Development 121:693705.
  • Park EJ, Watanabe Y, Smyth G, Miyagawa-Tomita S, Meyers E, Klingensmith J, Camenisch T, Buckingham M, Moon AM. 2008. An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart. Development 135:35993610.
  • Perveen R, Lloyd IC, Clayton-Smith J, Churchill A, van Heyningen V, Hanson I, Taylor D, McKeown C, Super M, Kerr B, Winter R, Black GC. 2000. Phenotypic variability and asymmetry of Rieger syndrome associated with PITX2 mutations. Invest Ophthalmol Vis Sci 41:24562460.
  • Ray HJ, Niswander L. 2012. Mechanisms of tissue fusion during development. Development 139:17011711.
  • Romano LA, Runyan RB. 2000. Slug is an essential target of TGFbeta2 signaling in the developing chicken heart. Dev Biol 223:91102.
  • Schnabel RB. 2011. Comparison of approaches to fine-map first-generation genome-wide association study results at chromosome 9p21. Circ Cardiovasc Genet 4:577578.
  • Shih HP, Gross MK, Kioussi C. 2007a. Cranial muscle defects of Pitx2 mutants result from specification defects in the first branchial arch. Proc Natl Acad Sci USA 104:59075912.
  • Shih HP, Gross MK, Kioussi C. 2007b. Expression pattern of the homeodomain transcription factor Pitx2 during muscle development. Gene Expr Patterns 7:441451.
  • Tessari A, Pietrobon M, Notte A, Cifelli G, Gage PJ, Schneider MD, Lembo G, Campione M. 2008. Myocardial Pitx2 differentially regulates the left atrial identity and ventricular asymmetric remodeling programs. Circ Res 102:813822.
  • Tirosh-Finkel L, Elhanany H, Rinon A, Tzahor E. 2006. Mesoderm progenitor cells of common origin contribute to the head musculature and the cardiac outflow tract. Development 133:19431953.
  • Verzi MP, McCulley DJ, De Val S, Dodou E, Black BL. 2005. The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart field. Dev Biol 287:134145.
  • Vitelli F, Morishima M, Taddei I, Lindsay EA, Baldini A. 2002. Tbx1 mutation causes multiple cardiovascular defects and disrupts neural crest and cranial nerve migratory pathways. Human Mol Genet 11:915922.
  • Waldo K, Miyagawa-Tomita S, Kumiski D, Kirby ML. 1998. Cardiac neural crest cells provide new insight into septation of the cardiac outflow tract: aortic sac to ventricular septal closure. Dev Biol 196:129144.
  • Waldo KL, Lo CW, Kirby ML. 1999. Connexin 43 expression reflects neural crest patterns during cardiovascular development. Dev Biol 208:307323.
  • Waldo KL, Hutson MR, Stadt HA, Zdanowicz M, Zdanowicz J, Kirby ML. 2005. Cardiac neural crest is necessary for normal addition of the myocardium to the arterial pole from the secondary heart field. Dev Biol 281:6677.
  • Webb S, Qayyum SR, Anderson RH, Lamers WH, Richardson MK. 2003. Septation and separation within the outflow tract of the developing heart. J Anat 202:327342.
  • Xu H, Morishima M, Wylie JN, Schwartz RJ, Bruneau BG, Lindsay EA, Baldini A. 2004. Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract. Development 131:32173227.
  • Yashiro K, Shiratori H, Hamada H. 2007. Haemodynamics determined by a genetic programme govern asymmetric development of the aortic arch. Nature 450:285288.
  • Zhou W, Lin L, Majumdar A, Li X, Zhang X, Liu W, Etheridge L, Shi Y, Martin J, Van de Ven W, Kaartinen V, Wynshaw-Boris A, McMahon AP, Rosenfeld MG, Evans SM. 2007. Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2. Nat Genet 39:12251234.