Expression of Neurogenin 1 in Mouse Embryonic Stem Cells Directs the Differentiation of Neuronal Precursors and Identifies Unique Patterns of Down-stream Gene Expression

Authors

  • J. Matthew Velkey,

    1. Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan
    2. Department of Cell Biology, Duke University, Durham, North Carolina
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  • K. Sue O'Shea

    Corresponding author
    • Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan
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Correspondence to: K.S. O'Shea, Department of Cell and Developmental Biology, University of Michigan Medical School, 109 Zina Pitcher Place, 3051 BSRB, Ann Arbor, MI 48109-2200. E-mail: oshea@umich.edu

Abstract

COVER PHOTOGRAPH: Neuronal differentiation of tet-inducible Neurogenin1-expressing ES cells 3 days after transgene induction, stained with antibodies recognizing Sox3 (green) and neuron-specific class III b-tubulin (amber); nuclei stained with Hoechst 33258 (blue). From Expression of Neurogenin 1 in Mouse Embryonic Stem Cells Directs the Differentiation of Neuronal Precursors and Identifies Unique Patterns of Down-stream Gene Expression, Matthew Velkey and Sue O'Shea, Developmental Dynamics 242:230–253, 2013.

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