Failure of centrosome migration causes a loss of motile cilia in talpid3 mutants

Authors

  • Louise A. Stephen,

    1. Division of Developmental Biology, The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, United Kingdom
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    • Authors' contributions: LAS undertook dissection, immunocytochemistry, confocal imaging, manuscript writing and intellectual contribution and design. GMD undertook dissection, immunocytochemistry and confocal imaging. KEM undertook dissection, RNA in situ hybridisation, confocal imaging. JJ undertook sample processing and imaging for EM. MK undertook sample processing and imaging for SEM. AB undertook sample processing, OPT imaging and image processing. LM undertook dissection, immunocytochemistry, histological analysis. MGD conceived the study, undertook dissection, immunocytochemistry, confocal imaging manuscript writing and intellectual contribution.

  • Gemma M. Davis,

    1. Division of Developmental Biology, The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, United Kingdom
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  • Katie E. Mcteir,

    1. Division of Developmental Biology, The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, United Kingdom
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  • John James,

    1. Central Microscope Facility, College of Life Sciences, University of Dundee, United Kingdom
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  • Lynn Mcteir,

    1. Division of Developmental Biology, The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, United Kingdom
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  • Martin Kierans,

    1. Central Microscope Facility, College of Life Sciences, University of Dundee, United Kingdom
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  • Andrew Bain,

    1. eChick Atlas, Division of Genetics and Genomics, The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, United Kingdom
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  • Megan G. Davey

    Corresponding author
    1. Division of Developmental Biology, The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, United Kingdom
    • Correspondence to: Megan G. Davey, Division of Developmental Biology, The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, UK EH25 9RG. E-mail: megan.davey@roslin.ed.ac.uk

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  • Competing interests: The authors do not have any competing interests.

Abstract

COVER PHOTOGRAPH: Electron microscopy image of ependymal cells of the telencephalic ChP. From Failure of centrosome migration causes a loss of motile cilia in talpid3 mutants, Louise A. Stephen, Gemma M. Davis, Katie E. McTeir, John James, Lynn McTeir, Martin Kierans, Andrew Bain, Megan G. Davey, Developmental Dynamics 242:923–931.

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