Distinct roles of MicroRNAs in epithelium and mesenchyme during tooth development (pages 1465–1472)
Shelly Oommen, Yoko Otsuka-Tanaka, Najam Imam, Maiko Kawasaki, Katsushige Kawasaki, Farnoosh Jalani-Ghazani, Angela Anderegg, Rajeshwar Awatramani, Robert Hindges, Paul T. Sharpe and Atsushi Ohazama
Article first published online: 24 JUL 2012 | DOI: 10.1002/dvdy.23828
Extra incisor tooth formation was found in ShhCre/Dicerfl/fl mice.
Wnt1Cre/Dicerfl/fl mice showed an arrest or absence of teeth development, which varied in frequency between incisors and molars.
Microarray an in situ hybridization analysis identified several miRNAs that showed differential expression between incisors and molars.