You have free access to this content

Developmental Dynamics

Cover image for Vol. 242 Issue 10

October 2013

Volume 242, Issue 10

Pages C1–C1, 1121–1221

  1. Cover Image

    1. Top of page
    2. Cover Image
    3. Art Pix
    4. Research Articles
    5. Techniques
    6. Patterns & Phenotypes
    1. You have free access to this content
      Canonical Wnt signaling regulates Nkx3.1 expression and luminal epithelial differentiation during prostate organogenesis (page C1)

      Marianna Kruithof-de Julio, Maho Shibata, Nishita Desai, Melissa Reynon, M. Vivienne Halili, Ya-Ping Hu, Sandy M. Price, Cory Abate-Shen and Michael M. Shen

      Version of Record online: 20 SEP 2013 | DOI: 10.1002/dvdy.24058

  2. Art Pix

    1. Top of page
    2. Cover Image
    3. Art Pix
    4. Research Articles
    5. Techniques
    6. Patterns & Phenotypes
    1. You have free access to this content
      DD ArtPix

      Version of Record online: 20 SEP 2013 | DOI: 10.1002/dvdy.24057

  3. Research Articles

    1. Top of page
    2. Cover Image
    3. Art Pix
    4. Research Articles
    5. Techniques
    6. Patterns & Phenotypes
    1. You have free access to this content
      Stress induces plant somatic cells to acquire some features of stem cells accompanied by selective chromatin reorganization (pages 1121–1133)

      Assa Florentin, Meytal Damri and Gideon Grafi

      Version of Record online: 24 JUL 2013 | DOI: 10.1002/dvdy.24003

      Key Findings

      • Acute stress induces, in leaf cells, the activity of a meristem-specific promoter derived from the ANAC2 transcription factor-encoding gene.
      • Stressed leaf cells acquire a dedifferentiated state characterized by open chromatin conformation.
      • Stress-induced chromatin decondensation is selective for peri-centromeric but not centromeric region.
      • Maintenance of hetrochromatin at centromeric region is not dependent on DNA and histone methylation driven by DDM1 and KYP/SUVH4 proteins.
    2. You have free access to this content
      Cell segregation, mixing, and tissue pattern in the spinal cord of the Xenopus laevis neurula (pages 1134–1146)

      Anna F. Edlund, Lance A. Davidson and Raymond E. Keller

      Version of Record online: 5 AUG 2013 | DOI: 10.1002/dvdy.24004

      Key findings

      • The neural tube floor in Xenopus laevis is flanked by superficial cells but composed of deep cells. The roof is composed of superficial cells, including some displaced from more ventral positions. In the tube's side walls, superficial cells are scattered among deep cells.
      • Cells do not mix into or out of the notoplate, which is a segregated population. Throughout the neural ectoderm, mediolateral intercalation is conservative, so that cells do not mix far from their cohorts, by this mechanism.
      • Cells can, however, be carried away from original neighbors by radial intercalation between deep and superficial layers, and such displaced cells appear to change gene expression profile.
    3. You have full text access to this OnlineOpen article
      Analysis of gene expression in wild-type and Notch1 mutant retinal cells by single cell profiling (pages 1147–1159)

      Karolina Mizeracka, Jeffrey M. Trimarchi, Michael B. Stadler and Constance L. Cepko

      Version of Record online: 2 SEP 2013 | DOI: 10.1002/dvdy.24006

      Key findings

      • Profiling of individual Notch1-mutant and wild-type postnatal retinal cells on microarrays reveals changes in gene expression obscured by whole tissue analysis.
      • Notch1-mutant cells down-regulate progenitor and cell cycle markers with a concomitant up-regulation in early rod photoreceptor markers.
      • Based on classification, single Notch1-mutant and wild-type cells represent transition from progenitor to postmitotic cell.
      • Individual wild-type retinal cells express cell type markers of both photoreceptors and interneurons.
    4. You have free access to this content
      Canonical Wnt signaling regulates Nkx3.1 expression and luminal epithelial differentiation during prostate organogenesis (pages 1160–1171)

      Marianna Kruithof-de Julio, Maho Shibata, Nishita Desai, Melissa Reynon, M. Vivienne Halili, Ya-Ping Hu, Sandy M. Price, Cory Abate-Shen and Michael M. Shen

      Version of Record online: 29 JUL 2013 | DOI: 10.1002/dvdy.24008

      Key findings

      • During prostate budding, Wnt activity occurs in both mesenchyme and epithelium.
      • Nkx3.1 expression in developing prostate is regulated by the canonical Wnt pathway.
      • Nkx3.1 is required to maintain canonical Wnt activity in prostate epithelium.
      • Canonical Wnts and Nkx3.1 regulate prostate ductal growth and differentiation.
    5. You have free access to this content
      Formation of the digestive tract in Ciona intestinalis includes two distinct morphogenic processes between its anterior and posterior parts (pages 1172–1183)

      Keiichi Nakazawa, Takumi Yamazawa, Yuuta Moriyama, Yosuke Ogura, Narudo Kawai, Yasunori Sasakura and Hidetoshi Saiga

      Version of Record online: 29 JUL 2013 | DOI: 10.1002/dvdy.24009

      Key findings

      • In Ciona intestinalis, the basic architecture of the digestive tract is formed by the stage35 when the tadpole tail is absorbed.
      • The anterior digestive tract, including the oesophagus and the stomach, is formed through the folding and closure of the endoderm.
      • The posterior digestive tract, the intestine, is formed through accumulation and rearrangement of the cells of the endodermal strand origin.
    6. You have free access to this content
      Complex cardiac defects after ethanol exposure during discrete cardiogenic events in zebrafish: Prevention with folic acid (pages 1184–1201)

      Swapnalee Sarmah and James A. Marrs

      Version of Record online: 2 SEP 2013 | DOI: 10.1002/dvdy.24015

      Key Findings

      • Zebrafish FASD model showed that ethanol interrupts multiple steps of cardiogenesis.
      • Ethanol exposure during zebrafish cardiogenesis produces persistent heart defects.
      • Chronic ethanol exposure during cardiogenesis produces complex cardiac defects.
      • Retinoic acid co-supplementation partially rescues ethanol-induced cardiac defects.
      • Folic acid co-supplementation prevents a wide spectrum of ethanol-induced heart defects.
  4. Techniques

    1. Top of page
    2. Cover Image
    3. Art Pix
    4. Research Articles
    5. Techniques
    6. Patterns & Phenotypes
    1. You have free access to this content
      Laser-mediated cell ablation during post-implantation mouse development (pages 1202–1209)

      Jesse R. Angelo and Kimberly D. Tremblay

      Version of Record online: 2 SEP 2013 | DOI: 10.1002/dvdy.24017

      Key findings

      • We establish parameters for laser ablation that, in conjunction with post-implantation mouse embryo culture, allows for normal development.
      • Laser ablation produces a controlled and immediate disruption of cells on the outside of the developing embryo without altering adjacent tissue layers or the underlying extracellular matrix.
      • Ablation of one of the three previously identified liver bud progenitor domains results in a unilateral delay in liver budding, demonstrating that laser ablation can be used to study cell fate in the mouse.
  5. Patterns & Phenotypes

    1. Top of page
    2. Cover Image
    3. Art Pix
    4. Research Articles
    5. Techniques
    6. Patterns & Phenotypes
    1. You have free access to this content
      Expression of insulin-like growth factor binding proteins during mouse cochlear development (pages 1210–1221)

      Takayuki Okano and Matthew W. Kelley

      Version of Record online: 2 SEP 2013 | DOI: 10.1002/dvdy.24005

      Key findings

      • Temporal and spatial expression patterns of Igfbps in the developing mouse cochlea were studied.
      • Igfbp2–5 are expressed during cochlear development, and the expression of each Igfbp increases significantly between E13.5 and P0.
      • Igfbp2–5 are expressed in unique and distinct patterns during cochlear development.

SEARCH

SEARCH BY CITATION