You have free access to this content

Developmental Dynamics

Cover image for Vol. 243 Issue 3

March 2014

Volume 243, Issue 3

Pages C1–C1, 357–508

  1. Cover Image

    1. Top of page
    2. Cover Image
    3. Critical Commentary
    4. Research Articles
    5. Patterns & Phenotypes
    1. You have free access to this content
      Irx4 identifies a chamber-specific cell population that contributes to ventricular myocardium development (page C1)

      Daryl O. Nelson, Dexter X. Jin, Karen M. Downs, Timothy J. Kamp and Gary E. Lyons

      Version of Record online: 18 FEB 2014 | DOI: 10.1002/dvdy.24045

  2. Critical Commentary

    1. Top of page
    2. Cover Image
    3. Critical Commentary
    4. Research Articles
    5. Patterns & Phenotypes
    1. You have free access to this content
      Day-1 chick development (pages 357–367)

      Guojun Sheng

      Version of Record online: 29 NOV 2013 | DOI: 10.1002/dvdy.24087

  3. Research Articles

    1. Top of page
    2. Cover Image
    3. Critical Commentary
    4. Research Articles
    5. Patterns & Phenotypes
    1. You have free access to this content
      Neural crest-derived cells sustain their multipotency even after entry into their target tissues (pages 368–380)

      Tsutomu Motohashi, Daisuke Kitagawa, Natsuki Watanabe, Takanori Wakaoka and Takahiro Kunisada

      Version of Record online: 23 NOV 2013 | DOI: 10.1002/dvdy.24072

      Key findings

      • NC-derived cells in skin, DRG, and inner ear are divided into 2 populations: Sox10+/Kit- cells and Sox10+/Kit+ cells.
      • Sox10+/Kit- cells in the skin and Sox10+/Kit+ cells in DRGs and inner ear are previously unidentified NC-derived cells.
      • The NC-derived Sox10+/Kit+ cells maintain their multipotency even after having entered the target tissues.
      • The differentiation potency of NC-derived cells in tissues is restricted depending on the tissue environment.
    2. You have free access to this content
      Irx4 identifies a chamber-specific cell population that contributes to ventricular myocardium development (pages 381–392)

      Daryl O. Nelson, Dexter X. Jin, Karen M. Downs, Timothy J. Kamp and Gary E. Lyons

      Version of Record online: 2 DEC 2013 | DOI: 10.1002/dvdy.24078

      Key findings

      • Ventricular myocardium specification occurs in the cardiac crescent.
      • IRX4+ cells in the cardiac crescent co-express markers of both heart fields.
      • IRX4 exhibits dynamic intracellular localization in maturing cardiomyocytes.
    3. You have free access to this content
      Regulation of cuticle pigmentation in drosophila by the nutrient sensing insulin and TOR signaling pathways (pages 393–401)

      Iryna Shakhmantsir, Nicole L. Massad and Jennifer A. Kennell

      Version of Record online: 7 NOV 2013 | DOI: 10.1002/dvdy.24080

      Key findings

      • Nutritional status during pupation regulates adult cuticle pigmentation in Drosophila melanogaster.
      • Insulin signaling in the underlying epidermal cells positively regulates cuticle pigmentation through PI3K/Akt and FOXO.
      • TOR signaling through S6K is a positive regulator of cuticle melanization.
    4. You have free access to this content
      Origin and specification of the brain leucokinergic neurons of Drosophila: Similarities to and differences from abdominal leucokinergic neurons (pages 402–414)

      Pilar Herrero, Alicia Estacio-Gómez, Marta Moris-Sanz, Javier Alvarez-Rivero and Fernando J. Diaz-Benjumea

      Version of Record online: 3 DEC 2013 | DOI: 10.1002/dvdy.24083

      Key Findings

      • The leucokinergic neurons of the lateral horn (LHLK) have an embryonic origin.
      • The temporal transcription factor Castor determines the origin of the LHLKs, from the protocerebrum neuroblast.
      • Many of the genetic characteristics of LHLKs are shared by the leucokinergic neurons in the abdominal segments of the ventral nerve, the ABLKs.
      • LHLKs and ABLKs originate from serially homologous neuroblasts in the protocerebrum and ventral ganglion.
    5. You have free access to this content
      Angiotensin II type 2 receptor regulates the development of pancreatic endocrine cells in mouse embryos (pages 415–427)

      Kwan Keung Leung, Juan Liang, Shuiling Zhao, Wood Yee Chan and Po Sing Leung

      Version of Record online: 23 NOV 2013 | DOI: 10.1002/dvdy.24084

      Key findings

      • Differential expression of AT1 and AT2 receptors was identified in mouse pancreas during pancreatic development.
      • AT2 receptor, but not AT1 receptor, blockade during the second transition stage of pancreatic development altered islet cell composition and impaired both insulin secretory function of neonatal islets and glucose tolerance of the pups.
      • Pancreas explants ex vivo data showed that AT2 receptors were essential for the differentiation of pancreatic progenitors into insulin producing cells, as well as for proliferation of the differentiated cells.
      • No evidence was found to suggest that AT2 receptor regulation of β-cell development is a secondary effect of angiotensin II-induced vascular endothelial growth factor–driven angiogenesis.
  4. Patterns & Phenotypes

    1. Top of page
    2. Cover Image
    3. Critical Commentary
    4. Research Articles
    5. Patterns & Phenotypes
    1. You have free access to this content
      Dact gene expression profiles suggest a role for this gene family in integrating Wnt and TGF-β signaling pathways during chicken limb development (pages 428–439)

      Lucimara Aparecida Sensiate, Débora R. Sobreira, Fernanda Cristina Da Veiga, Denner Jefferson Peterlini, Angelica Vasconcelos Pedrosa, Thaís Rirsch, Paulo Pinto Joazeiro, Frank R. Schubert, Carla Beatriz Collares-Buzato, José Xavier-Neto, Susanne Dietrich and Lúcia Elvira Alvares

      Version of Record online: 11 MAY 2013 | DOI: 10.1002/dvdy.23948

      Key findings

      • Dact1 and Dact2 are dynamically expressed during early chondrogenesis in sites that either overlap or complement Sox9 expression domains.
      • Dact1 and Dact2 are coexpressed in developing joints, tendons, and digit blastemas.
      • Dact1 mRNAs colocalize with nuclear β-catenin protein while Dact2 complements sites of bmpR-1b expression in developing synovial joints of digits.
    2. You have free access to this content
      Conditional ablation of Tbr2 results in abnormal development of the olfactory bulbs and subventricular zone-rostral migratory stream (pages 440–450)

      Robert J. Kahoud, Gina E. Elsen, Robert F. Hevner and Rebecca D. Hodge

      Version of Record online: 29 NOV 2013 | DOI: 10.1002/dvdy.24090

      Key Findings:

      • Conditional deletion of Tbr2 results in hypoplasia of the olfactory bulb and defects in the generation of olfactory bulb projection neurons (mitral cells).
      • Development of the subventricular zone and rostral migratory stream is disrupted by Tbr2 ablation.
      • Adult glutamatergic neurogenesis from the SVZ is impaired following specific ablation of Tbr2 in the adult brain.
    3. You have free access to this content
      Piwi regulates Vasa accumulation during embryogenesis in the sea urchin (pages 451–458)

      Mamiko Yajima, Eric A. Gustafson, Jia L. Song and Gary M. Wessel

      Version of Record online: 2 DEC 2013 | DOI: 10.1002/dvdy.24096

      Key findings

      • Piwi knockdown results in Vasa over-expression during embryogenesis.
      • Piwi is important for proper PGC proliferation.
      • Piwi functions outside of germ line during embryogenesis.
    4. You have free access to this content
      ENU-3 functions in an UNC-6/netrin dependent pathway parallel to UNC-40/DCC/frazzled for outgrowth and guidance of the touch receptor neurons in C. elegans (pages 459–467)

      Callista Yee, Roxana Florica, Jeffrey Fillingham and Marie T. Killeen

      Version of Record online: 25 DEC 2013 | DOI: 10.1002/dvdy.24063

      Key findings

      • ENU-3 and UNC-40 work in parallel to guide AVMs and DTCs in an UNC-6 dependent pathway.
      • Outgrowth defects of DB motor neuron axons in the absence of UNC-5 depend on the presence of UNC-40.
      • DB outgrowth defects are enhanced by absence of ENU-3, and UNC-5, and the presence of UNC-40.
    5. You have full text access to this OnlineOpen article
      Pou5f1 protein expression and posttranslational modification during early zebrafish development (pages 468–477)

      Bernadette Lippok, Sungmin Song and Wolfgang Driever

      Version of Record online: 21 NOV 2013 | DOI: 10.1002/dvdy.24079

      Key findings

      • New antibody reveals Pou5f1 protein distribution during zebrafish early development.
      • Pou5f1 protein temporal profile correlates with pluripotent cell state during gastrulation.
      • Pou5f1 protein is deposited in oocyte.
      • Pou5f1 is present in extraembryonic enveloping layer, but not in yolk syncytial nuclei.
      • Pou5f1 is subject to multiple phosphorylations which prevail during late gastrula stages.
    6. You have free access to this content
      Novel animal pole-enriched maternal mRNAs are preferentially expressed in neural ectoderm (pages 478–496)

      Paaqua A. Grant, Bo Yan, Michael A. Johnson, Diana L.E. Johnson and Sally A. Moody

      Version of Record online: 21 DEC 2013 | DOI: 10.1002/dvdy.24082

      Key Findings

      • Maternal mRNAs are enriched in animal blastomeres of Xenopus laevis.
      • Many of these are later enriched in neural plate, neural crest, placodes and neural tube.
      • The developmental expression patterns of 14 novel genes are provided.
    7. You have free access to this content
      Embryonic expression of the transforming growth factor beta ligand and receptor genes in chicken (pages 497–508)

      James R. Cooley, Tatiana A. Yatskievych and Parker B. Antin

      Version of Record online: 2 DEC 2013 | DOI: 10.1002/dvdy.24085

      Key findings

      • Expression patterns of the TGFB ligands and receptors were examined in chicken embryos during the first four days of development.
      • TGFB ligands and receptors show dynamic and frequently overlapping expression patterns in numerous embryonic cell layers and structures.
      • Integrating expression information identifies combinations of ligands and receptors that are involved in specific developmental processes including somitogenesis, cardiogenesis and vasculogenesis.

SEARCH

SEARCH BY CITATION