Sara A. Colopy, Dale E. Bjorling, William A. Mulligan and Wade Bushman
Version of Record online: 23 JUL 2014 | DOI: 10.1002/dvdy.24050
Cover legend: A population of progenitor cells in the basal and intermediate layers of the murine bladder urothelium contributes to urothelial development and regeneration. Co-staining with Krt5 (green) and Krt20 (red) in the left-hand panels demonstrated loss of the superficial cell layer following bacterial inoculation. Rare Krt20+ superficial cells were identified 1 day post-inoculation. By 3 days post-inoculation, Krt20 staining was present within the majority of the luminal cell layer, indicating renewal of differentiated superficial cells. From Colopy et al, Developmental Dynamics, 243:988–998.