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Keywords:

  • AVE;
  • embryology;
  • anterior;
  • patterning;
  • migration

Abstract

The Anterior Visceral Endoderm is an extraembryonic tissue that plays a pivotal role during embryogenesis, being responsible for the proper orientation of the anterior-posterior axis of the embryo and for appropriate pattering of adjacent embryonic tissue. In this review I discuss the formation and migration of the AVE, and attempt to place some recent findings in the context of a working model. genesis 44:565–572, 2006. © 2006 Wiley-Liss, Inc.