Craniofacial Embryogenetics and Development, ed. 2 by G.H. Sperber and S.M. Sperber, and G.D. Guttman, ( 2010). People's Medical Publishing House, Shelton, CT. ISBN-13 978-1-60795-032-5.

Kurt E. Johnson PhD*, * Professor of Anatomy and Regenerative Biology The George Washington University School of Medicine Washington, DC.

The field of craniofacial developmental genetics has garnered a great deal of attention as the basic and clinical sciences intersect to understand normal development and the underlying causes of craniofacial birth defects. Thus, the recent publication of the second edition of Craniofacial Embryogenetics and Development, by Sperber, Sperber, and Guttman, is very timely.

This excellent book is divided into two main sections. The first section reviews basic human embryology and craniofacial development. The second section focuses on specific topics of craniofacial development, e.g., the facial skeleton, the mandible, the temporomandibular joint, development of dentition, and so forth. Each chapter is richly illustrated and contains a wealth of information on the developmental anatomy of a selected region of the head and neck as well as a comprehensive review of the genetic basis of the control of normal and abnormal morphogenesis. There are also extensive reading lists provided as references for each chapter. The book ends with a concise tabulated summary of craniofacial disorders attributable to single gene mutations, compiled by G.A. Mackin, and a succinct glossary.

This book should be required reading for craniofacial surgeons and pediatricians specializing in analysis and treatment of patients with craniofacial birth defects. In addition, research scientists and graduate students interested in learning the current state of affairs on the genetic control of craniofacial development will find this book quite useful. The book also provides access to a website that contains both a collection of ancillary images and ancillary videos. The images are merely electronic versions of the book's illustrations that may be useful to users who wish to incorporate them into lectures and presentations. The videos are three-dimensional renderings of various parts of the embryo. Although colorful and rotating in space to give different views, they are not labeled and therefore hard to interpret for all but the most expert viewer. Labels at the beginning of the videos would be most helpful to give a better understanding to novices in this complex field. Aside from this small criticism, overall, this book is an important contribution to the field of craniofacial morphogenesis and dysmorphogenesis and is highly recommended.