Restoration of ovarian and uterine maturity in adolescents with anorexia nervosa
Article first published online: 23 AUG 2002
Copyright © 2002 Wiley Periodicals, Inc.
International Journal of Eating Disorders
Volume 32, Issue 3, pages 319–325, November 2002
How to Cite
Key, A., Mason, H., Allan, R. and Lask, B. (2002), Restoration of ovarian and uterine maturity in adolescents with anorexia nervosa. Int. J. Eat. Disord., 32: 319–325. doi: 10.1002/eat.10087
- Issue published online: 23 AUG 2002
- Article first published online: 23 AUG 2002
- Manuscript Accepted: 30 SEP 2001
- anorexia nervosa;
- pelvic ultrasound;
- ovarian/uterine maturity
To determine the optimal weight-to-height ratio to achieve maturity of the reproductive organs when visualized by pelvic ultrasound in adolescent girls with anorexia nervosa. To examine the distribution of weight-to-height ratios in the group of adolescents in whom pelvic maturity was attained.
Adolescent girls with anorexia nervosa received serial transabdominal pelvic ultrasound scans as they regained weight. A record of their weight-to-height ratio had been noted on each occasion. The scans were defined as mature or immature using strict criteria.
There was a wide range of weight-to-height ratios in both the mature and immature groups of patients with a considerable overlap between the groups. However, 88% of the sample required a weight-to-height ratio of 100% (body mass index [BMI] 20) to achieve reproductive maturity.
Previous target weights have been too low to ensure reproductive maturity. The resulting hypoestrogenic state increases the risk of future osteoporosis. Pelvic ultrasound is the safest and most reliable method for determining ovarian and uterine maturity in adolescent girls with anorexia nervosa. © 2002 by Wiley Periodicals, Inc. Int J Eat Disord 32: 319–325, 2002.