Central pontine myelinolysis in a patient with anorexia nervosa
Version of Record online: 16 OCT 2001
Copyright © 2001 John Wiley & Sons, Inc.
International Journal of Eating Disorders
Volume 30, Issue 4, pages 462–466, December 2001
How to Cite
Amann, B., Schäfer, M., Sterr, A., Arnold, S. and Grunze, H. (2001), Central pontine myelinolysis in a patient with anorexia nervosa. Int. J. Eat. Disord., 30: 462–466. doi: 10.1002/eat.1109
- Issue online: 16 OCT 2001
- Version of Record online: 16 OCT 2001
- pontine myelinolysis;
- water intoxication
Myelinolysis may occur as a severe complication of eating disorders, especially anorexia nervosa (AN). One of the most important reasons can be a rapid correction of hyponatremia caused by tubulopathy, water intoxication (WI), or abuse of diuretics in individuals with AN.
Method and Results
We report on a 24-year-old female patient with an 8-year history of AN. A rapid correction of severe hyponatremia and hypokalemia induced by WI led to central pontine myelinolysis, which was confirmed by magnetic resonance imaging (MRI) examination. Besides affective lability, incoherence, and an acute confusional state, surprisingly, no severe neurological symptoms emerged.
Thus, physicians should be aware of the risk of pontine myelinolysis with new psychiatric symptoms emerging in the absence of obvious neurological deficits. © 2001 by John Wiley & Sons, Inc. Int J Eat Disord 30: 462–466, 2001.