Osteoporosis in Chinese patients with anorexia nervosa

Authors

  • Samuel Wong,

    Corresponding author
    1. Jockey Club Centre for Osteoporosis Care and Control, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
    • 3/F, Jockey Club Centre for Osteoporosis Care and Control, School of Public Health, Prince of Wales Hospital, Shatin, N.T
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  • Betty Au,

    1. Jockey Club Centre for Osteoporosis Care and Control, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
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  • Edith Lau,

    1. Department of Community and Family Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
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  • Yvonne Lee,

    1. Jockey Club Centre for Osteoporosis Care and Control, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
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  • Aprille Sham,

    1. Department of Community and Family Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
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  • Sing Lee

    1. Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
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Abstract

Objective

A case-control study was conducted to determine whether bone mass is reduced in Chinese patients with anorexia nervosa (AN) and to study the risk factors for low bone mass in the same population.

Method

Bone mineral density (BMD) of the lumbar spine and hip was measured by dual-energy X-ray absorptiometry in 42 AN patients and 221 controls.

Results

Patients with AN had a significantly lower BMD in the total hip and spine compared with controls (p < .001). In AN patients, linear regression showed that lowest body mass index (BMI) was positively associated with BMD in the hip (p = .04) whereas duration of illness was negatively associated with BMD in the hip (p = .05).

Discussion

Chinese patients with AN are at risk of low BMD. Duration of illness and lowest BMI were significant predictors of reduced BMD in Chinese patients with AN. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 36: 104–108, 2004.

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