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Keywords:

  • anorexia nervosa;
  • morbidity;
  • treatment research

Abstract

In spite of much being written on the treatment of anorexia nervosa (AN), and the well-documented long-term morbidity of this illness, treatment effects have been little investigated. The current article considers the prospects for treatment research, taking note of the formidable challenges that lie ahead for the design, implementation, and interpretation of controlled clinical trials, and highlighting opportunities for effectiveness studies. In the light of increasing evidence of the role played by biologic susceptibility factors in AN, the potential future contribution to treatment research of advances in pharmacogenetics and molecular neuroscience also receives comment. © 2005 by Wiley Periodicals, Inc.