Pharmacologic treatment of anorexia nervosa: Where do we go from here?
Article first published online: 25 APR 2005
Copyright © 2005 Wiley Periodicals, Inc.
International Journal of Eating Disorders
Special Issue: Special Issue on Anorexia Nervosa
Volume 37, Issue S1, pages S60–S63, 2005
How to Cite
Attia, E. and Schroeder, L. (2005), Pharmacologic treatment of anorexia nervosa: Where do we go from here?. Int. J. Eat. Disord., 37: S60–S63. doi: 10.1002/eat.20133
- Issue published online: 25 APR 2005
- Article first published online: 25 APR 2005
- Manuscript Accepted: 29 DEC 2004
- anorexia nervosa;
- eating disorders;
Anorexia nervosa (AN) is a serious mental disorder, characterized by severely low weight and cognitive distortions about body shape and weight. AN is generally associated with a range of psychological symptoms, including depression, anxiety, obsessions, and rituals. The current study summarized findings from randomized controlled trials (RCT) using pharmacologic treatments in patients with AN. We conducted a review of literature using Medline. Several classes of pharmacologic agents have been studied in small samples of patients with acute AN without finding clear benefit to eating, weight, body shape concerns, or associated psychopathology. Studies have been limited by small sample sizes, as well as by research design with most studies adding medication to comprehensive hospital-based treatment programs. Future directions for pharmacologic treatment research in AN should include outpatient trials, rigorous study of atypical antipsychotic medication, and assessment of medication effect for relapse prevention in weight-restored patients. © 2005 by Wiley Periodicals, Inc.