Disclaimer: The authors of this report are responsible for its content. Statements in the report should not be construed as endorsement by the Agency for Healthcare Research and Quality or the U.S. Department of Health and Human Services of a particular drug, device, test, treatment, or other clinical service.
Special Section Article
Outcomes of eating disorders: A systematic review of the literature†
Article first published online: 16 MAR 2007
Copyright © 2007 Wiley Periodicals, Inc.
International Journal of Eating Disorders
Volume 40, Issue 4, pages 293–309, May 2007
How to Cite
Berkman, N. D., Lohr, K. N. and Bulik, C. M. (2007), Outcomes of eating disorders: A systematic review of the literature. Int. J. Eat. Disord., 40: 293–309. doi: 10.1002/eat.20369
- Issue published online: 28 MAR 2007
- Article first published online: 16 MAR 2007
- Manuscript Accepted: 5 DEC 2006
- Agency for Healthcare Research and Quality. Grant Number: 290-02-0016
- systematic review;
- anorexia nervosa;
- bulimia nervosa;
- binge eating disorder;
- eating disorders;
- cohort study;
- obsessive-compulsive disorder
The RTI International-University of North Carolina at Chapel Hill Evidence-based Practice Center systematically reviewed evidence on factors associated with outcomes among individuals with anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED) and whether outcomes differed by sociodemographic characteristics.
We searched electronic databases including MEDLINE and reviewed studies published from 1980 to September, 2005, in all languages against a priori inclusion/exclusion criteria and focused on eating, psychiatric or psychological, or biomarker outcomes.
At followup, individuals with AN were more likely than comparisons to be depressed, have Asperger's syndrome and autism spectrum disorders, and suffer from anxiety disorders including obsessive-compulsive disorders. Mortality risk was significantly higher than what would be expected in the population and the risk of suicide was particularly pronounced. The only consistent factor across studies relating to worse BN outcomes was depression. A substantial proportion of individuals continue to suffer from eating disorders over time but BN was not associated with increased mortality risk. Data were insufficient to draw conclusions concerning factors associated with BED outcomes. Across disorders, little to no data were available to compare results based on sociodemographic characteristics.
The strength of the bodies of literature was moderate for factors associated with AN and BN outcomes and weak for BED. © 2007 by Wiley Periodicals, Inc. Int J Eat Disord 2007