Neuropsychological study of underweight and “weight-recovered” anorexia nervosa compared with bulimia nervosa and normal controls

Authors


  • Parts of manuscript have been presented at British Association of Psychopharmacology Meeting 2003, CINP 2004, RANZCP Congress 2005, and 2nd Asian Pacific Eating Disorders Meeting 2005.

Abstract

Objective:

To compare executive, memory and visuospatial functioning of DSM-IV anorexia nervosa (AN), bulimia nervosa (BN), and normal controls (NC).

Method:

A comparison of women involving: (i) 16 AN with body mass indices (BMI) ≤ 17.5 kg/m2; (ii) 12 AN with BMI > 18.5 kg/m2 for at least 3 months; (iii) 13 BN; and (iv) 16 NC participants was performed with groups of similar age and intelligence. Groups were assessed with EDE-12, MADRS, HAMA, Cognitive Drug Research (CDR) battery, and Bechara tasks.

Results:

Significant impairments in CDR Power of Attention were present in underweight AN and BN participants. CDR Morse Tapping was significantly impaired in all clinical groups. The BN and weight-recovered AN groups were significantly impaired on CDR immediate word recall. The BN group alone was significantly impaired on CDR delayed word recall.

Conclusion:

Attentional impairment is similar in AN and BN. Impaired motor tasks in AN persist after “weight-recovery” and are similar to impairments in BN. BN may be discriminated from AN on word recall. © 2007 by Wiley Periodicals, Inc. Int J Eat Disord 2007

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