Are obsessive-compulsive personality traits associated with a poor outcome in anorexia nervosa? A systematic review of randomized controlled trials and naturalistic outcome studies
Article first published online: 2 JUL 2007
Copyright © 2007 Wiley Periodicals, Inc.
International Journal of Eating Disorders
Volume 40, Issue 7, pages 581–588, November 2007
How to Cite
Crane, A. M., Roberts, M. E. and Treasure, J. (2007), Are obsessive-compulsive personality traits associated with a poor outcome in anorexia nervosa? A systematic review of randomized controlled trials and naturalistic outcome studies. Int. J. Eat. Disord., 40: 581–588. doi: 10.1002/eat.20419
- Issue published online: 26 SEP 2007
- Article first published online: 2 JUL 2007
- Manuscript Accepted: 13 MAY 2007
- anorexia nervosa;
- systematic review
Obsessive-compulsive personality disorder (OCPD) traits are commonly associated with anorexia nervosa (AN). The aim of this review was to systematically search the literature to examine whether OCPD traits have an impact on the outcome of AN.
A systematic electronic search of the literature (using Medline, PsycINFO, and the Cochrane Central Register of Controlled Trials) was undertaken to identify relevant publications (randomized controlled trials (RCT's) and naturalistic studies), until February 2006.
Eleven prospective longitudinal studies and 12 RCT's met criteria for inclusion. A meta-analysis was not feasible as the studies were too heterogeneous. Just over half of published longitudinal studies found that OCPD traits were associated with a negative outcome in AN. Additionally, results from three RCTs suggested that these traits may moderate outcome. OCPD traits were reduced after treatment in five RCTs.
There is tentative support to suggest that individuals with AN and concomitant OCPD traits have a poorer prognosis, and that these traits moderate outcome. A reduction in these traits may mediate this change. An individualized case formulation with treatment tailored to OCPD traits may improve the outcome of AN. © 2007 by Wiley Periodicals, Inc.