The duration of severe insulin omission is the factor most closely associated with the microvascular complications of Type 1 diabetic females with clinical eating disorders
Article first published online: 19 DEC 2007
Copyright © 2007 Wiley Periodicals, Inc.
International Journal of Eating Disorders
Volume 41, Issue 3, pages 259–264, April 2008
How to Cite
Takii, M., Uchigata, Y., Tokunaga, S., Amemiya, N., Kinukawa, N., Nozaki, T., Iwamoto, Y. and Kubo, C. (2008), The duration of severe insulin omission is the factor most closely associated with the microvascular complications of Type 1 diabetic females with clinical eating disorders. Int. J. Eat. Disord., 41: 259–264. doi: 10.1002/eat.20498
- Issue published online: 28 FEB 2008
- Article first published online: 19 DEC 2007
- Manuscript Accepted: 15 SEP 2007
- Japan Society for the Promotion of Science. Grant Number: 15590599
- Japan Study Group for Pediatric and Adolescent Diabetes
- binge eating;
- eating disorders;
- insulin omission;
- risk factor;
- Type 1 diabetes
To investigate which features of eating disorders are associated with retinopathy and nephropathy in Type 1 diabetic females with clinical eating disorders.
Participants were 109 Type 1 diabetic females with clinical eating disorders diagnosed by the structured clinical interview for DSM-IV (bulimia nervosa [n = 70], binge-eating disorder [n = 28], anorexia nervosa [n = 7], and eating disorder not otherwise specified [n = 4]). Retinopathy and nephropathy were screened and demographic, medical, and eating disorder related factors were investigated. To identify the factors associated with each complication, logistic regression analysis was done.
Duration of severe insulin omission and duration of Type 1 diabetes were significantly associated with retinopathy (odds ratios = 1.35 and 1.23, respectively) and nephropathy (odds ratio = 1.35 and 1.21, respectively) in multivariate regression analyses.
Of the various problematic behavioral factors related to eating disorders, the duration of severe insulin omission was the factor most closely associated with the retinopathy and nephropathy of Type 1 diabetic females with clinical eating disorders by multivariate analysis. This finding may help patients who deliberately omit insulin become aware of medical risk of insulin omission. © 2007 by Wiley Periodicals, Inc. Int J Eat Disord, 2008