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Regular Article
Assessment of HRQoL in patients with eating disorders by the beta-binomial regression approach
Article first published online: 17 JUN 2009
DOI: 10.1002/eat.20713
Copyright © 2009 Wiley Periodicals, Inc.
Additional Information
How to Cite
Arostegui, I., Padierna, A. and Quintana, J. M. (2010), Assessment of HRQoL in patients with eating disorders by the beta-binomial regression approach. International Journal of Eating Disorders, 43: 455–463. doi: 10.1002/eat.20713
Publication History
- Issue published online: 1 JUN 2010
- Article first published online: 17 JUN 2009
- Manuscript Accepted: 30 APR 2009
Funded by
- Department of Health of the Basque Country. Grant Number: UPV 100.310-EA81808/2000
- Universidad del País Vasco (UPV/EHU). Grant Numbers: MTM2004-00341, MTM2007-60112
- Ministerio Español de Educación y Ciencia and FEDER
- CIBER Epidemiología y Salud Pública, CIBERESP, Spain
- Abstract
- References
- Cited By
Keywords:
- beta-binomial regression;
- prospective study;
- predictors;
- quality of life
Abstract
Objective:
To study the influence of clinical variables on health-related quality of life (HRQoL) among women with eating disorder (ED) using beta-binomial regression (BBR) to analyze scores on the Short-Form 36 (SF-36) as dependent variable.
Method:
Female patients diagnosed with ED completed the SF-36 at the beginning of the study and after 2 years of treatment. Sociodemographic and clinical information was recorded. For the multivariate analysis, we used BBR models to identify factors that influence SF-36.
Results:
Questionnaires were completed by 193 women at baseline and 158 (82%) after 2 years of treatment. Anxiety, depression, and the severity of ED, explained scores in most domains of the SF-36 at baseline. The main predictor of HRQoL after 2 years of follow-up was the HRQoL in the same domain at baseline. However, depression, anxiety, and duration of symptoms at baseline also significantly influenced HRQoL after 2 years of treatment in some domains. Higher levels of anxiety or depression, longer duration of symptoms, and poorer SF-36 scores at baseline were associated with worse HRQoL after 2 years of treatment and follow-up.
Discussion:
BBR models provide understandable results for clinicians and can be used in multivariate models with HRQoL dependent variables. © 2009 by Wiley Periodicals, Inc. Int J Eat Disord 2010