Aripiprazole in anorexia nervosa and low-weight bulimia nervosa: Case reports
Article first published online: 22 FEB 2010
Copyright © 2010 Wiley Periodicals, Inc.
International Journal of Eating Disorders
Volume 44, Issue 3, pages 269–275, April 2011
How to Cite
Trunko, M. E., Schwartz, T. A., Duvvuri, V. and Kaye, W. H. (2011), Aripiprazole in anorexia nervosa and low-weight bulimia nervosa: Case reports. Int. J. Eat. Disord., 44: 269–275. doi: 10.1002/eat.20807
- Issue published online: 22 FEB 2010
- Article first published online: 22 FEB 2010
- Manuscript Accepted: 20 DEC 2009
- anorexia nervosa;
- bulimia nervosa;
- atypical antipsychotics;
- long-term follow up;
There has been much interest in the use of atypical antipsychotics in anorexia nervosa (AN). However, newer, more weight-neutral medications have not been studied in AN, and there are no reports of the use of antipsychotics in bulimia nervosa (BN).
We report on the treatment of eight patients (five with AN and three with BN) with aripiprazole for time periods of four months to more than three years.
All individuals had reduced distress around eating, fewer obsessional thoughts about food, weight and body image, significant lessening of eating-disordered behaviors, and gradual weight restoration where appropriate. Depression, generalized anxiety, and cognitive flexibility improved as well.
In summary, these findings support the need to perform controlled trials of aripiprazole in AN and BN. © 2010 by Wiley Periodicals, Inc. (Int J Eat Disord 2011; 44:269–275)