Normal late ventricular potentials in hospitalized patients with eating disorders

Authors

  • Moshe Nussinovitch MD,

    1. Department of Pediatrics C, Schneider Children's Medical Center of Israel, Petach Tikva
    2. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
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  • Eitan Gur MD,

    1. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    2. Eating Disorder Department, Sheba Medical Center, Tel Hashomer, Israel
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  • Keren Kaminer MD,

    1. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
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  • Benjamin Volovitz MD,

    1. Department of Pediatrics C, Schneider Children's Medical Center of Israel, Petach Tikva
    2. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
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  • Naomi Nussinovitch MD,

    1. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    2. Hypertension Unit and Department of Internal Medicine D, Chaim Sheba Medical Center Tel Hashomer, Israel
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    • N.N. and U.N. contributed equally to this work.

  • Udi Nussinovitch MD

    Corresponding author
    1. The Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    • The Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel 52620
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    • N.N. and U.N. contributed equally to this work.


Abstract

Objective:

Eating disorders, in particular anorexia nervosa (AN), are associated with cardiovascular complications and risk of arrhythmias. In a recent published study, it was found that patients with eating disorders, especially those affected by bulimia nervosa (BN) and a history of AN have abnormal late ventricular potentials (LPs). LPs are electrocardiographic markers used in detecting abnormal depolarization and increased risk of arrhythmias. Given the paucity of knowledge regarding the affects of eating disorders on cardiac depolarization, our aim was to further explore LPs in patients with eating disorders.

Method:

The study group included 30 hospitalized patients with eating disorders (14 with AN, 10 with BN with no history of AN, and 6 with BN and history of AN). Signal averaged electrocardiography was conducted on all patients usingthe Frank corrected orthogonal lead system.

Results:

No patient with either eating disorder tested positive for LPs.

Discussion:

Hospitalized patients with eating disorders, medically monitored and treated for several weeks, had normal serum electrolytes, started to normalize their weight, and did not appear to be prone to arrhythmias associated with abnormal depolarization. The prognostic significance of LPs in risk stratification of patients with eating disorders should be further evaluated by large cohort studies and longer follow-up studies. © 2011 by Wiley Periodicals, Inc. (Int J Eat Disord 2011;45:900–904)

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