Severe anorexia nervosa in men: Comparison with severe AN in women and analysis of mortality

Authors

  • Juliette Gueguen MD,

    1. Inserm, U669, Paris, France
    2. Univ Paris-Sud and Univ Paris Descartes, UMR-S0669, Paris, France
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  • Nathalie Godart MD, PhD,

    1. Inserm, U669, Paris, France
    2. Univ Paris-Sud and Univ Paris Descartes, UMR-S0669, Paris, France
    3. Institut Mutualiste Montsouris, Paris, France
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  • Jean Chambry MD,

    1. Inserm, U669, Paris, France
    2. Univ Paris-Sud and Univ Paris Descartes, UMR-S0669, Paris, France
    3. AP-HP, Hôpital Kremlin Bicêtre, Department of Pedospychiatry, Kremlin Bicêtre, France
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  • Annick Brun-Eberentz MD,

    1. Hôpital Sainte-Anne, Clinique des maladies mentales et de l'encéphale, Paris, France
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  • Christine Foulon MD,

    1. Inserm, U669, Paris, France
    2. Univ Paris-Sud and Univ Paris Descartes, UMR-S0669, Paris, France
    3. Hôpital Sainte-Anne, Clinique des maladies mentales et de l'encéphale, Paris, France
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  • Snezana M. Divac, PhD,

    1. Hôpital Sainte-Anne, Clinique des maladies mentales et de l'encéphale, Paris, France
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  • Julien-Daniel Guelfi MD,

    1. Hôpital Sainte-Anne, Clinique des maladies mentales et de l'encéphale, Paris, France
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  • Frédéric Rouillon MD,

    1. Univ Paris-Sud and Univ Paris Descartes, UMR-S0669, Paris, France
    2. Hôpital Sainte-Anne, Clinique des maladies mentales et de l'encéphale, Paris, France
    3. Center Psychiatry and Neurosciences Inserm U894, Paris, France
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  • Bruno Falissard MD, PhD,

    1. Inserm, U669, Paris, France
    2. Univ Paris-Sud and Univ Paris Descartes, UMR-S0669, Paris, France
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  • Caroline Huas MD, PhD

    Corresponding author
    1. Inserm, U669, Paris, France
    2. Univ Paris-Sud and Univ Paris Descartes, UMR-S0669, Paris, France
    3. Univ Tours, Department of General Practice, 37000 Tours, France
    • Univ Paris-Sud and Univ Paris Descartes, UMR-S0669, Paris
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Abstract

Objective:

To compare clinical characteristics of men and women with severe AN and to analyze mortality in men.

Method:

One thousand and nine patients including 23 anorectic males were hospitalized in St. Anne Hospital in Paris between 1988 and 2004. Data were collected during hospitalization. Fatal outcome was assessed in 2008.

Results:

Men presented significantly later age of onset, were more likely to have a history of premorbid overweight than women and less likely to have attempted suicide. Mortality in men was high (standardized mortality ratio: 8.08; 95% CI: 1.62–23.62). Several predictive factors for mortality in men were identified: lower admission body mass index (BMI), later age at admission, and AN-R subtype. All the three deceased patients had dropped out from the inpatient unit. The 10-year survival did not differ between men and women, but men died sooner after hospitalization.

Discussion:

Male inpatients should receive close follow-up after their discharge, especially if they have a restrictive form of AN, present low BMI, or are older at admission. © 2012 by Wiley Periodicals, Inc. (Int J Eat Disord 2012)

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