Supported by 01/01/2010-12/31/12 2009–3146 from Swedish Research Council project grant number and by 01/01/2008-12/31/11 2007–2064 from the Swedish Council for Working Life and Social Research project grant number.
Parental mental illness and eating disorders in offspring
Article first published online: 25 JUN 2014
© 2014 Wiley Periodicals, Inc.
International Journal of Eating Disorders
Volume 48, Issue 4, pages 383–391, May 2015
How to Cite
Bould, H., Koupil, I., Dalman, C., DeStavola, B., Lewis, G. and Magnusson, C. (2015), Parental mental illness and eating disorders in offspring. Int. J. Eat. Disord., 48: 383–391. doi: 10.1002/eat.22325
- Issue published online: 9 APR 2015
- Article first published online: 25 JUN 2014
- Manuscript Accepted: 14 JUN 2014
- Manuscript Revised: 27 MAY 2014
- Manuscript Received: 28 AUG 2013
- eating disorders;
- anorexia nervosa;
- bulimia nervosa;
- mental illness
To investigate which parental mental illnesses are associated with eating disorders in their offspring.
We used data from a record-linkage cohort study of 158,679 children aged 12–24 years at the end of follow-up, resident in Stockholm County from 2001 to 2007, to investigate whether different parental mental illnesses are risk factors for eating disorders in their offspring. The outcome measure was diagnosis of any eating disorder, either from an ICD or DSM-IV code, or inferred from an appointment at a specialist eating disorder clinic.
Mental illness in parents is a risk factor for eating disorders in female offspring (Adjusted Hazard Ratio (AHR) 1.57 (95% CI 1.42, 1.92), p < 0.0001). Risk of eating disorders is increased if there is a parental diagnosis of bipolar affective disorder (AHR 2.28 (95% CI 1.39, 3.72), p = 0.004), personality disorder (AHR 1.57 (95% CI 1.01, 2.44), p = 0.043) or anxiety/depression (AHR 1.57 (95% CI 1.32, 1.86), p < 0.0001). There is a lack of statistical evidence for an association with parental schizophrenia (AHR 1.41 (95% CI 0.96, 2.07), p = 0.08), and somatoform disorder (AHR 1.25 (95% CI 0.74, 2.13), p = 0.40). There is no support for a relationship between parental substance misuse and eating disorders in children (AHR 1.08 (95% CI 0.82, 1.43), p = 0.57).
Parental mental illness, specifically parental anxiety, depression, bipolar affective disorder, and personality disorders, are risk factors for eating disorders in their offspring. © 2014 Wiley Periodicals, Inc. (Int J Eat Disord 2015; 48:383–391)