Lisa Kotler, M.D., a recent graduate of Yale University School of Medicine, is currently an intern in psychiatry at Mt. Sinai Hospital, New York.
Case study of the effects of prolonged and severe anorexia nervosa on bone mineral density
Article first published online: 1 SEP 2010
Copyright © 1994 Wiley Periodicals, Inc., A Wiley Company
International Journal of Eating Disorders
Volume 15, Issue 4, pages 395–399, May 1994
How to Cite
Kotler, L., Katz, L., Anyan, W. and Comite, F. (1994), Case study of the effects of prolonged and severe anorexia nervosa on bone mineral density. Int. J. Eat. Disord., 15: 395–399. doi: 10.1002/eat.2260150410
- Issue published online: 1 SEP 2010
- Article first published online: 1 SEP 2010
- Manuscript Accepted: 27 AUG 1993
Among the most severe sequelae of anorexia nervosa (AN) are its skeletal complications. Young women who have AN during adolescence may not attain their expected peak skeletal mass, and may enter adulthood with reduced bone mineral density (BMD) and an increased risk of fracture. This case history describes a young woman with severe AN that included prolonged exposure to both low body weight and amenorrhea. BMD measurement during the acute stage of her illness revealed severe osteopenia. Six years after recovery from AN, follow-up studies demonstrated only modest gains in BMD, with measurements for the hip and lumbar spine that are greater than 2 SDs below the age-matched mean.