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  • Reference to included reviews
  • Fernandes RM, Bialy LM, Vandermeer B, Tjosvold L, Plint AC, Patel H, et al. Glucocorticoids for acute viral bronchiolitis in infants and young children. Cochrane Database Syst Rev 2010; Issue (10): Art. No.: CD004878. DOI: 10.1002/14651858.CD004878.pub3.
  • Hartling L, Bialy LM, Vandermeer B, Tjosvold L, Johnson DW, Plint AC, et al. Epinephrine for bronchiolitis. Cochrane Database Syst Rev 2011; Issue (6): Art. No.: CD003123. DOI: 10.1002/14651858.CD003123.pub3.
  • References to trials in included reviews
  • Epinephrine trials:
  • Abul-Ainine A, Luyt D. Short term effects of adrenaline in bronchiolitis: a randomised controlled trial. Arch Dis Child 2002; 86: 276279.
  • Barlas C, Kiper N, Gocmen A, Ozcelik U, Dilber E, Anadol D, et al. Racemic adrenaline and other treatment regimens in mild and moderate bronchiolitis. Cocuk Sagligi Ve Hastaliklari Dergisi 1998; 41: 155165.
  • Bertrad P, Aranibar H, Castro E, Sanchez I. Efficacy of nebulized epinephrine versus salbutamol in hospitalised infants with bronchiolitis. Pediatr Pulmonol 2001; 31: 284288.
  • Hariprakash S, Alexander J, Carroll W, Ramesh P, Randell T, Turnbull F, Lenney W. Randomized controlled trial of nebulized adrenaline in acute bronchiolitis. Pediatr Allergy Immunol 2003; 14: 16.
  • Kristjansson S, Lodrup Carlsen KC, Wennergren G, Strannegard I-L, Carlsen K-H. Nebulised racemic adrenaline in the treatment of acute bronchiolitis in infants and toddlers. Arch Dis Child 1993; 69: 650654.
  • Lowell DI, Lister G, Von Koss H, McCarthy P. Wheezing in infants: the response to epinephrine. Pediatrics 1987; 79: 939945.
  • Menon K, Sutcliffe T, Klassen TP. A randomised trial comparing the efficacy of epinephrine with salbutamol in the treatment of acute bronchiolitis. J Pediatr 1995; 126: 10041007.
  • Mull CC, Scarfone RJ, Ferri LR, Carlin T, Salvaggio C, Bechtel KA, et al.Nebulized epinephrine in the emergency department treatment of bronchiolitis. Abstract presented at the Annual Meeting of the American Pediatric Society and the Society for Pediatric Research, Baltimore, MD, May 2002.
  • Okutan V, Akin R, Kurekci AE, Yanik A, Ozcan O, Gokcay E. Effectiveness of nebulised adrenaline and salbutamol in the treatment of infants with bronchiolitis. Bull Gulhane Military Med Acad 1998; 40: 199204.
  • Patel H, Platt RW, Pekeles GS, Ducharme F. Randomized, controlled trial of extended-use epinephrine in infants with bronchiolitis. Abstract presented at the Annual Meeting of the American Pediatric Society and the Society for Pediatric Research, 2001, Baltimore Convention Center, Baltimore, USA.
  • Ray MS, Singh V. Comparison of nebulized adrenaline versus salbutamol in wheeze associated respiratory tract infection in infants. Ind Pediatr 2002; 39: 1222.
  • Reijonen T, Korppi M, Pitkakangas S, Tenhola S, Remes K. The clinical efficacy of nebulized racemic epinephrine and albuterol in acute bronchiolitis. Arch Pediatr Adolesc Med 1995; 149: 686692.
  • Sanchez I, De Koster J, Powell RE, Wolstein R, Chernick V. Effect of racemic epinephrine and salbutamol on clinical score and pulmonary mechanics in infants with bronchiolitis. J Pediatr 1993; 122: 145151.
  • Wainwright C, Altamirano L, Cheney M, Cheney J, Barber S, Price D, et al. A multi-centre randomised controlled double blind trial of nebulised adrenaline in infants with bronchiolitis. N Engl J Med 2003; 349: 2735.
  • Glucocorticoid trials:
  • Barlas C, Kiper N, Göçmen A, Ozçelik U, Dilber E, Anadol D, et al. Racemic adrenaline and other treatment regimens in mild and moderate bronchiolitis. Cocuk Sagligi Ve Hastaliklari Dergisi 1998; 41: 155166.
  • Bentur L, Shoseyov D, Feigenbaum D, Gorichovsky Y, Bibi H. Dexamethasone inhalations in RSV bronchiolitis: a double-blind, placebo-controlled study. Acta Paediatrica 2005; 94: 866871.
  • Berger I, Argaman Z, Schwartz SB, Segal E, Kiderman A, Branski D, et al. Efficacy of glucocorticoids in acute bronchiolitis: short-term and long-term follow-up. Pediatr Pulmonol 1998; 26: 162166.
  • Cade A, Brownlee KG, Conway SP, Haigh D, Short A, Brown J, et al. Randomised placebo controlled trial of nebulised glucocorticoids in acute respiratory syncytial viral bronchiolitis. Arch Dis Child 2000; 82: 126130.
  • Corneli HM, Zorc JJ, Mahajan P, Shaw KN, Holubkov R, Reeves SD, et al. A multicenter, randomized, controlled trial of dexamethasone for bronchiolitis. NEJM 2007; 357: 331339.
  • De Boeck K, Van der Aa N, Van Lierde S, Corbeel L, Eeckels R. Respiratory syncytial virus bronchiolitis: a double-blind dexamethasone efficacy study. J Pediatr 1997; 131: 919921.
  • Goebel J, Estrada B, Quinonez J, Nagi N, Sanford D, Boerth RC. Prednisolone plus albuterol versus albuterol alone in mild to moderate bronchiolitis. Clin Pediatr 2000; 39: 213220.
  • Gomez-y-Lopez RE, Hernandez-Sierra JF, Torres-Ruvalcaba BA, Martinez-Puente E, del Carmen Martinez-Garcia M. Comparative clinical study of dexamethasone vs. nebulized salbutamol in acute bronchiolitis. Gaceta Medica de Mexico 2007; 143: 189192.
  • Klassen TP, Sutcliffe T, Watters LK, Wells GA, Allen UD, Li MM. Dexamethasone in salbutamol-treated inpatients with acute bronchiolitis: a randomized, controlled trial. J Pediatr 1997; 130: 191196.
  • Kuyucu S, Unal S, Kuyucu N, Yilgor E. Additive effects of dexamethasone in nebulized salbutamol or L-epinephrine treated infants with acute bronchiolitis. Pediatr Int 2004; 46: 539544.
  • Mesquita M, Castro-Rodriguez JA, Heinichen L, Fariña E, Iramain R. Single oral dose of dexamethasone in outpatients with bronchiolitis: a placebo controlled trial. Allergologia et Immunopathologia 2009; 37: 6367.
  • Plint AC, Johnson DW, Patel H, Wiebe N, Correll R, Brant R, et al. Epinephrine and dexamethasone in children with bronchiolitis. NEJM 2009; 360: 20792089.
  • Richter H, Seddon P. Early nebulized budesonide in the treatment of bronchiolitis and the prevention of postbronchiolitic wheezing. J Pediatr 1998; 132: 849853.
  • Roosevelt G, Sheehan K, Grupp-Phelan J, Tanz RR, Listernic R. Dexamethasone in bronchiolitis: a randomised controlled trial. Lancet 1996; 348: 292305.
  • Schuh S, Coates AL, Binnie R, Allin T, Goia C, Corey M, et al. Efficacy of oral dexamethasone in outpatients with acute bronchiolitis. J Pediatr 2002; 140: 2732.
  • Teeratakulpisarn J, Limwattananon C, Tanupattarachai S, Limwattananon S, Teeratakulpisarn S, Kosalaraksa P. Efficacy of dexamethasone injection for acute bronchiolitis in hospitalized children: a randomized, double-blind, placebo-controlled trial. Pediatr Pulmonol 2007; 42: 433439.
  • Zhang L, Ferruzzi E, Bonfanti T, Auler MI, D'Avila NE, Faria CS, et al. Long and short-term effect of prednisolone in hospitalized infants with acute bronchiolitis. J Paediatr Child Health 2003; 39: 548551.