• 1
    Zlotnik, A. and Yoshie, O., Chemokines: A new classification system and their role in immunity. Immunity 2000. 12: 121127.
  • 2
    Norment, A. M., Bogatzki, L. Y., Gantner, B. N. and Bevan, M. J., Murine CCR9, a chemokine receptor for thymus-expressed chemokine that is up-regulated following pre-TCR signaling. J. Immunol. 2000. 164: 639648.
  • 3
    Zabel, B. A., Agace, W. W., Campbell, J. J., Heath, H. M., Parent, D., Roberts, A. I., Ebert, E. C. et al., Human G protein-coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis. J. Exp. Med. 1999. 190: 12411256.
  • 4
    Zaballos, A., Gutierrez, J., Varona, R., Ardavin, C. and Marquez, G., Cutting edge: Identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK. J. Immunol. 1999. 162: 56715675.
  • 5
    Vicari, A. P., Figueroa, D. J., Hedrick, J. A., Foster, J. S., Singh, K. P., Menon, S., Copeland, N. G. et al., TECK: A novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development. Immunity 1997. 7: 291301.
  • 6
    Youn, B. S., Kim, C. H., Smith, F. O. and Broxmeyer, H. E., TECK, an efficacious chemoattractant for human thymocytes, uses GPR-9-6/CCR9 as a specific receptor. Blood 1999. 94: 25332536.
  • 7
    Wurbel, M. A., Philippe, J. M., Nguyen, C., Victorero, G., Freeman, T., Wooding, P., Miazek, A. et al., The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double- and single-positive thymocytes expressing the TECK receptor CCR9. Eur. J. Immunol. 2000. 30: 262271.
  • 8
    Campbell, J. J., Pan, J. and Butcher, E. C., Cutting edge: Developmental switches in chemokine responses during T cell maturation. J. Immunol. 1999. 163: 23532357.
  • 9
    Wurbel, M. A., Malissen, M., Guy-Grand, D., Meffre, E., Nussenzweig, M. C., Richelme, M., Carrier, A. and Malissen, B., Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor gammadelta(+) gut intraepithelial lymphocytes. Blood 2001. 98: 26262632.
  • 10
    Uehara, S., Grinberg, A., Farber, J. M. and Love, P. E., A role for CCR9 in T lymphocyte development and migration. J. Immunol. 2002. 168: 28112819.
  • 11
    Shortman, K. and Wu, L., Early T lymphocyte progenitors. Annu. Rev. Immunol. 1996. 14: 2947.
  • 12
    Malissen, B., Ardouin, L., Lin, S. Y., Gillet, A. and Malissen, M., Function of the CD3 subunits of the pre-TCR and TCR complexes during T cell development. Adv. Immunol. 1999. 72: 103148.
  • 13
    Berlin, C., Bargatze, R. F., Campbell, J. J., von Andrian, U. H., Szabo, M. C., Hasslen, S. R., Nelson, R. D. et al., Alpha 4 integrins mediate lymphocyte attachment and rolling under physiologic flow. Cell 1995. 80: 413422.
  • 14
    Plotkin, J., Prockop, S. E., Lepique, A. and Petrie, H. T., Critical role for CXCR4 signaling in progenitor localization and T cell differentiation in the postnatal thymus. J. Immunol. 2003. 171: 45214527.
  • 15
    Gabor, M. J., Godfrey, D. I. and Scollay, R., Recent thymic emigrants are distinct from most medullary thymocytes. Eur. J. Immunol. 1997. 27: 20102015.
  • 16
    Martin, C. H., Aifantis, I., Scimone, M. L., von Andrian, U. H., Reizis, B., von Boehmer, H. and Gounari, F., Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential. Nat. Immunol. 2003. 4: 866873.
  • 17
    Schwarz, B. A. and Bhandoola, A., Circulating hematopoietic progenitors with T lineage potential. Nat. Immunol. 2004. 5: 953960.
  • 18
    Canelles, M., Park, M. L., Schwartz, O. M. and Fowlkes, B. J., The influence of the thymic environment on the CD4-versus-CD8 T lineage decision. Nat. Immunol. 2003. 4: 756764.
  • 19
    Benz, C., Heinzel, K. and Bleul, C. C., Homing of immature thymocytes to the subcapsular microenvironment within the thymus is not an absolute requirement for T cell development. Eur. J. Immunol. 2004. 34: 36523663.
  • 20
    Olaussen, R. W., Farstad, I. N., Brandtzaeg, P. and Rugtveit, J., Age-related changes in CCR9+ circulating lymphocytes: Are CCR9+ naive T cells recent thymic emigrants? Scand. J. Immunol. 2001. 54: 435439.
  • 21
    Staton, T. L., Johnston, B., Butcher, E. C. and Campbell, D. J., Murine CD8+ recent thymic emigrants are alphaE integrin-positive and CC chemokine ligand 25 responsive. J. Immunol. 2004. 172: 72827288.
  • 22
    Ericsson, A., Svensson, M., Arya, A. and Agace, W. W., CCL25/CCR9 promotes the induction and function of CD103 on intestinal intraepithelial lymphocytes. Eur. J. Immunol. 2004. 34: 27202729.
  • 23
    Kunkel, E. J., Campbell, J. J., Haraldsen, G., Pan, J., Boisvert, J., Roberts, A. I., Ebert, E. C. et al., Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity. J. Exp. Med. 2000. 192: 761768.
  • 24
    Mora, J. R., Bono, M. R., Manjunath, N., Weninger, W., Cavanagh, L. L., Rosemblatt, M. and Von Andrian, U. H., Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells. Nature 2003. 424: 8893.
  • 25
    Campbell, J. J., Bowman, E. P., Murphy, K., Youngman, K. R., Siani, M. A., Thompson, D. A., Wu, L. et al., 6-C-kine (SLC), a lymphocyte adhesion-triggering chemokine expressed by high endothelium, is an agonist for the MIP-3beta receptor CCR7. J. Cell Biol. 1998. 141: 10531059.
  • 26
    Chestukhin, A. and DeCaprio, J. A., Western blot screening for monoclonal antibodies against human separase. J. Immunol. Methods 2003. 274: 105113.