• 1
    Germain, R. N. and Margulies, D. H., The biochemistry and cell biology of antigen processing and presentation. Annu. Rev. Immunol. 1993. 11: 403450.
  • 2
    Porcelli, S. A., Morita, C. T. and Brenner, M. B., Cd1b restricts the response of human CD48 T lymphocytes to a microbial antigen. Nature 1992. 360: 593597.
  • 3
    De Libero, G. and Mori, L., Recognition of lipid antigens by T cells. Nat. Rev. Immunol. 2005. 5: 485496.
  • 4
    Moody, D. B., Zajonc, D. M. and Wilson, I. A., Anatomy of CD1-lipid antigen complexes. Nat. Rev. Immunol. 2005. 5: 387399.
  • 5
    Manolova, V., Hirabayashi, Y., Mori, L. and De Libero, G., CD1a and CD1b surface expression is independent from de novo synthesized glycosphingolipids. Eur. J. Immunol. 2003. 33: 2937.
  • 6
    Joyce, S., Woods, A. S., Yewdell, J. W., Bennink, J. R., De Silva, A. D., Boesteanu, A., Balk, S. P. et al., Natural ligand of mouse CD1d1: cellular glycosylphosphatidylinositol. Science 1998. 279: 15411544.
  • 7
    Jayawardena-Wolf, J., Benlagha, K., Chiu, Y. H., Mehr, R. and Bendelac, A., CD1d endosomal trafficking is independently regulated by an intrinsic CD1d-encoded tyrosine motif and by the invariant chain. Immunity 2001. 15: 897908.
  • 8
    Kang, S. J. and Cresswell, P., Regulation of intracellular trafficking of human CD1d by association with MHC class II molecules. EMBO J. 2002. 21: 16501660.
  • 9
    Altamirano, M. M., Woolfson, A., Donda, A., Shamshiev, A., Briseno-Roa, L., Foster, N. W., Veprintsev, D. B. et al., Ligand-independent assembly of recombinant human CD1 by using oxidative refolding chromatography. Proc. Natl. Acad. Sci. USA 2001. 98: 32883293.
  • 10
    Shamshiev, A., Gober, H. J., Donda, A., Mazorra, Z., Mori, L. and De Libero, G., Presentation of the same glycolipid by different CD1 molecules. J. Exp. Med. 2002. 195: 10131021.
  • 11
    Helms, J. B. and Rothman, J. E., Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF. Nature 1992. 360: 352354.
  • 12
    Poussin, C., Foti, M., Carpentier, J. L. and Pugin, J., CD14-dependent endotoxin internalization via a macropinocytic pathway. J. Biol. Chem. 1998. 273: 2028520291.
  • 13
    Parton, R. G., Joggerst, B. and Simons, K., Regulated internalization of caveolae. J. Cell Biol. 1994. 127: 11991215.
  • 14
    Sugita, M., Grant, E. P., van Donselaar, E., Hsu, V. W., Rogers, R. A., Peters, P. J. and Brenner, M. B., Separate pathways for antigen presentation by CD1 molecules. Immunity 1999. 11: 743752.
  • 15
    Salamero, J., Bausinger, H., Mommaas, A. M., Lipsker, D., Proamer, F., Cazenave, J.-P., Goud, B. et al., CD1a molecules traffic through the early recycling endosomal pathway in human Langerhans cells. J. Invest. Dermatol. 2001. 116: 401408.
  • 16
    Moody, D. B. and Porcelli, S. A., Intracellular pathways of CD1 antigen presentation. Nat. Rev. Immunol. 2003. 3: 1122.
  • 17
    Jackman, R. M., Stenger, S., Lee, A., Moody, D. B., Rogers, R. A., Niazi, K. R., Sugita, M. et al., The tyrosine-containing cytoplasmic tail of CD1b is essential for its efficient presentation of bacterial lipid antigens. Immunity 1998. 8: 341351.
  • 18
    Mc Dermott, R., Ziylan, U., Spehner, D., Bausinger, H., Lipsker, D., Mommaas, M., Cazenave, J. P. et al., Birbeck granules are subdomains of endosomal recycling compartment in human epidermal Langerhans cells, which form where Langerin accumulates. Mol. Biol. Cell 2002. 13: 317335.
  • 19
    Kefford, R. F., Calabi, F., Fearnley, I. M., Burrone, O. R. and Milstein, C., Serum beta 2-microglobulin binds to a T-cell differentiation antigen and increases its expression. Nature 1984. 308: 641642.
  • 20
    Bernabeu, C., van de Rijn, M., Lerch, P. G. and Terhorst, C. P., Beta 2-microglobulin from serum associates with MHC class I antigens on the surface of cultured cells. Nature 1984. 308: 642645.
  • 21
    Zajonc, D. M., Elsliger, M. A., Teyton, L. and Wilson, I. A., Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 A. Nat. Immunol. 2003. 29: 29.
  • 22
    Gadola, S. D., Zaccai, N. R., Harlos, K., Shepherd, D., Castro-Palomino, J. C., Ritter, G., Schmidt, R. R. et al., Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains. Nat. Immunol. 2002. 3: 721726.
  • 23
    Shamshiev, A., Donda, A., Carena, I., Mori, L., Kappos, L. and De Libero, G., Self glycolipids as T-cell autoantigens. Eur. J. Immunol. 1999. 29: 16671675.
  • 24
    Schumacher, T. N., Heemels, M. T., Neefjes, J. J., Kast, W. M., Melief, C. J. and Ploegh, H. L., Direct binding of peptide to empty MHC class I molecules on intact cells and invitro. Cell 1990. 62: 563567.
  • 25
    York, I. A. and Rock, K. L., Antigen processing and presentation by the class I major histocompatibility complex. Annu. Rev. Immunol. 1996. 14: 369396.
  • 26
    Rock, K. L., Gamble, S., Rothstein, L., Gramm, C. and Benacerraf, B., Dissociation of beta 2-microglobulin leads to the accumulation of a substantial pool of inactive class I MHC heavy chains on the cell surface. Cell 1991. 65: 611620.
  • 27
    Merrill, A. H., Jr., Lingrell, S., Wang, E., Nikolova-Karakashian, M., Vales, T. R. and Vance, D. E., Sphingolipid biosynthesis de novo by rat hepatocytes in culture. Ceramide and sphingomyelin are associated with, but not required for, very low density lipoprotein secretion. J. Biol. Chem. 1995. 270: 1383413841.
  • 28
    Moody, D. B., Young, D. C., Cheng, T.-Y., Rosat, J.-P., Roura-mir, C., O'Connor, P. B., Zajonc, D. M. et al., T cell activation by lipopeptide antigens. Science 2004. 303: 527531.
  • 29
    Rosat, J. P., Grant, E. P., Beckman, E. M., Dascher, C. C., Sieling, P. A., Frederique, D., Modlin, R. L. et al., CD1-restricted microbial lipid antigen-specific recognition found in the CD8+ alpha beta T cell pool. J. Immunol. 1999. 162: 366371.
  • 30
    Schaible, U. E., Hagens, K., Fischer, K., Collins, H. L. and Kaufmann, S. H., Intersection of group I CD1 molecules and mycobacteria in different intracellular compartments of dendritic cells. J. Immunol. 2000. 164: 48434852.
  • 31
    Lipsker, D., Ziylan, U., Spehner, D., Proamer, F., Bausinger, H., Jeannin, P., Bohbot, A. et al., Heat shock proteins 70 and 60 share common receptors which are expressed on human monocyte-derived but not epidermal dendritic cells. Eur. J. Immunol. 2002. 32: 322332.