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  • 1
    Adler, A. J., Huang, C. T., Yochum, G. S., Marsh, D. W. and Pardoll, D. M., In vivo CD4+ T cell tolerance induction versus priming is independent of the rate and number of cell divisions. J. Immunol. 2000. 164: 649655.
  • 2
    Kearney, E. R., Pape, K. A., Loh, D. Y. and Jenkins, M. K., Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1994. 1: 327339.
  • 3
    Schwartz, R. H., T cell anergy. Annu. Rev. Immunol. 2003. 21: 305334.
  • 4
    Steinman, R. M., Hawiger, D. and Nussenzweig, M. C., Tolerogenic dendritic cells. Annu. Rev. Immunol. 2003. 21: 685711.
  • 5
    Watts, T. H., TNF/TNFR family members in costimulation of T cell responses. Annu. Rev. Immunol. 2005. 23: 2368.
  • 6
    Gramaglia, I., Weinberg, A. D., Lemon, M. and Croft, M., Ox-40 ligand: a potent costimulatory molecule for sustaining primary CD4 T cell responses. J. Immunol. 1998. 161: 65106517.
  • 7
    Godfrey, W. R., Fagnoni, F. F., Harara, M. A., Buck, D. and Engleman, E. G., Identification of a human OX-40 ligand, a costimulator of CD4+ T cells with homology to tumor necrosis factor. J. Exp. Med. 1994. 180: 757762.
  • 8
    Chen, A. I., McAdam, A. J., Buhlmann, J. E., Scott, S., Lupher, M. L., Jr., Greenfield, E. A., Baum, P. R. et al., Ox40-ligand has a critical costimulatory role in dendritic cell:T cell interactions. Immunity 1999. 11: 689698.
  • 9
    Gramaglia, I., Jember, A., Pippig, S. D., Weinberg, A. D., Killeen, N. and Croft, M., The OX40 costimulatory receptor determines the development of CD4 memory by regulating primary clonal expansion. J. Immunol. 2000. 165: 30433050.
  • 10
    Jember, A. G., Zuberi, R., Liu, F. T. and Croft, M., Development of allergic inflammation in a murine model of asthma is dependent on the costimulatory receptor OX40. J. Exp. Med. 2001. 193: 387392.
  • 11
    Kopf, M., Ruedl, C., Schmitz, N., Gallimore, A., Lefrang, K., Ecabert, B., Odermatt, B. and Bachmann, M. F., OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL responses after virus infection. Immunity 1999. 11: 699708.
  • 12
    Murata, K., Ishii, N., Takano, H., Miura, S., Ndhlovu, L. C., Nose, M., Noda, T. and Sugamura, K., Impairment of antigen-presenting cell function in mice lacking expression of OX40 ligand. J. Exp. Med. 2000. 191: 365374.
  • 13
    Pippig, S. D., Pena-Rossi, C., Long, J., Godfrey, W. R., Fowell, D. J., Reiner, S. L., Birkeland, M. L. et al., Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40). J. Immunol. 1999. 163: 65206529.
  • 14
    Blazar, B. R., Sharpe, A. H., Chen, A. I., Panoskaltsis-Mortari, A., Lees, C., Akiba, H., Yagita, H. et al., Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients. Blood 2003. 101: 37413748.
  • 15
    Weinberg, A. D., Wegmann, K. W., Funatake, C. and Whitham, R. H., Blocking OX-40/OX-40 ligand interaction in vitro and in vivo leads to decreased T cell function and amelioration of experimental allergic encephalomyelitis. J. Immunol. 1999. 162: 18181826.
  • 16
    Arestides, R. S., He, H., Westlake, R. M., Chen, A. I., Sharpe, A. H., Perkins, D. L. and Finn, P. W., Costimulatory molecule OX40L is critical for both Th1 and Th2 responses in allergic inflammation. Eur. J. Immunol. 2002. 32: 28742880.
  • 17
    Evans, D. E., Prell, R. A., Thalhofer, C. J., Hurwitz, A. A. and Weinberg, A. D., Engagement of OX40 enhances antigen-specific CD4(+) T cell mobilization/memory development and humoral immunity: comparison of anti-OX-40 with anti-CTLA-4. J. Immunol. 2001. 167: 68046811.
  • 18
    Maxwell, J. R., Weinberg, A., Prell, R. A. and Vella, A. T., Danger and OX40 receptor signaling synergize to enhance memory T cell survival by inhibiting peripheral deletion. J. Immunol. 2000. 164: 107112.
  • 19
    Croft, M., Co-stimulatory members of the TNFR family: keys to effective T-cell immunity? Nat. Rev. Immunol. 2003. 3: 609620.
  • 20
    Weinberg, A. D., OX40: targeted immunotherapy--implications for tempering autoimmunity and enhancing vaccines. Trends Immunol. 2002. 23: 102109.
  • 21
    Weinberg, A. D., Rivera, M. M., Prell, R., Morris, A., Ramstad, T., Vetto, J. T., Urba, W. J. et al., Engagement of the OX-40 receptor in vivo enhances antitumor immunity. J. Immunol. 2000. 164: 21602169.
  • 22
    Bansal-Pakala, P., Jember, A. G. and Croft, M., Signaling through OX40 (CD134) breaks peripheral T-cell tolerance. Nat. Med. 2001. 7: 907912.
  • 23
    Rogers, P. R., Song, J., Gramaglia, I., Killeen, N. and Croft, M., OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells. Immunity 2001. 15: 445455.
  • 24
    Song, J., Salek-Ardakani, S., Rogers, P. R., Cheng, M., Van Parijs, L. and Croft, M., The costimulation-regulated duration of PKB activation controls T cell longevity. Nat. Immunol. 2004. 5: 150158.
  • 25
    Song, J., So, T., Cheng, M., Tang, X. and Croft, M., Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion. Immunity 2005. 22: 621631.
  • 26
    Walker, L. S., Gulbranson-Judge, A., Flynn, S., Brocker, T., Raykundalia, C., Goodall, M., Forster, R. et al., Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers. J. Exp. Med. 1999. 190: 11151122.
  • 27
    Lathrop, S. K., Huddleston, C. A., Dullforce, P. A., Montfort, M. J., Weinberg, A. D. and Parker, D. C., A signal through OX40 (CD134) allows anergic, autoreactive T cells to acquire effector cell functions. J. Immunol. 2004. 172: 67356743.
  • 28
    Kaleeba, J. A., Offner, H., Vandenbark, A. A., Lublinski, A. and Weinberg, A. D., The OX-40 receptor provides a potent co-stimulatory signal capable of inducing encephalitogenicity in myelin-specific CD4+ T cells. Int. Immunol. 1998. 10: 453461.
  • 29
    McIntyre, K. R. and Seidman, J. G., Nucleotide sequence of mutant I-Ab bm12 gene is evidence for genetic exchange between mouse immune response genes. Nature 1984. 308: 551553.
  • 30
    Brown, G. R., Lee, E. L. and Thiele, D. L., TNF enhances CD4+ T cell alloproliferation, IFN-γ responses, and intestinal graft-versus-host disease by IL-12-independent mechanisms. J. Immunol. 2003. 170: 50825088.
  • 31
    Gonzalez, M., Quezada, S. A., Blazar, B. R., Panoskaltsis-Mortari, A., Rudensky, A. Y. and Noelle, R. J., The balance between donor T cell anergy and suppression versus lethal graft-versus-host disease is determined by host conditioning. J. Immunol. 2002. 169: 55815589.
  • 32
    Yang, J., Zhu, H., Murphy, T. L., Ouyang, W. and Murphy, K. M., IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCR-induced, IFN-gamma production. Nat. Immunol. 2001. 2: 157164.
  • 33
    Martin-Orozco, N., Chen, Z., Poirot, L., Hyatt, E., Chen, A., Kanagawa, O., Sharpe, A. et al., Paradoxical dampening of anti-islet self-reactivity but promotion of diabetes by OX40 ligand. J. Immunol. 2003. 171: 69546960.
  • 34
    Kim, M. Y., Bekiaris, V., McConnell, F. M., Gaspal, F. M., Raykundalia, C. and Lane, P. J., OX40 signals during priming on dendritic cells inhibit CD4 T cell proliferation: IL-4 switches off OX40 signals enabling rapid proliferation of Th2 effectors. J. Immunol. 2005. 174: 14331437.
  • 35
    Blaser, B. W., Roychowdhury, S., Kim, D. J., Schwind, N. R., Bhatt, D., Yuan, W., Kusewitt, D. F. et al., Donor-derived IL-15 is critical for acute allogeneic graft-versus-host disease. Blood 2005. 105: 894901.
  • 36
    Kondrack, R. M., Harbertson, J., Tan, J. T., McBreen, M. E., Surh, C. D. and Bradley, L. M., Interleukin 7 regulates the survival and generation of memory CD4 cells. J. Exp. Med. 2003. 198: 17971806.
  • 37
    Malek, T. R., Yu, A., Scibelli, P., Lichtenheld, M. G. and Codias, E. K., Broad programming by IL-2 receptor signaling for extended growth to multiple cytokines and functional maturation of antigen-activated T cells. J. Immunol. 2001. 166: 16751683.
  • 38
    Vander Heiden, M. G., Plas, D. R., Rathmell, J. C., Fox, C. J., Harris, M. H. and Thompson, C. B., Growth factors can influence cell growth and survival through effects on glucose metabolism. Mol. Cell Biol. 2001. 21: 58995912.
  • 39
    Higgins, A. D., Mihalyo, M. A., McGary, P. W. and Adler, A. J., CD4 cell priming and tolerization are differentially programmed by APCs upon initial engagement. J. Immunol. 2002. 168: 55735581.
  • 40
    Weatherill, A. R., Maxwell, J. R., Takahashi, C., Weinberg, A. D. and Vella, A. T., OX40 ligation enhances cell cycle turnover of Ag-activated CD4 T cells in vivo. Cell Immunol. 2001. 209: 6375.
  • 41
    Song, A., Tang, X., Harms, K. M. and Croft, M., OX40 and Bcl-xL promote the persistence of CD8 T cells to recall tumor-associated antigen. J. Immunol. 2005. 175: 35343541.
  • 42
    Van Parijs, L., Peterson, D. A. and Abbas, A. K., The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens. Immunity 1998. 8: 265274.
  • 43
    Akiba, H., Miyahira, Y., Atsuta, M., Takeda, K., Nohara, C., Futagawa, T., Matsuda, H. et al., Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental leishmaniasis. J. Exp. Med. 2000. 191: 375380.
  • 44
    Ishii, N., Ndhlovu, L. C., Murata, K., Sato, T., Kamanaka, M. and Sugamura, K., OX40 (CD134) and OX40 ligand interaction plays an adjuvant role during in vivo Th2 responses. Eur. J. Immunol. 2003. 33: 23722381.
  • 45
    Mestas, J., Crampton, S. P., Hori, T. and Hughes, C. C., Endothelial cell co-stimulation through OX40 augments and prolongs T cell cytokine synthesis by stabilization of cytokine mRNA. Int. Immunol. 2005. 17: 737747.
  • 46
    Kelly, E., Won, A., Refaeli, Y. and Van Parijs, L., IL-2 and related cytokines can promote T cell survival by activating AKT. J. Immunol. 2002. 168: 597603.
  • 47
    Van Parijs, L., Refaeli, Y., Lord, J. D., Nelson, B. H., Abbas, A. K. and Baltimore, D., Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death. Immunity 1999. 11: 281288.
  • 48
    Deshpande, S., Zheng, M., Lee, S., Banerjee, K., Gangappa, S., Kumaraguru, U. and Rouse, B. T., Bystander activation involving T lymphocytes in herpetic stromal keratitis. J. Immunol. 2001. 167: 29022910.