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  • 1
    Vilches, C. and Parham, P., KIR: Diverse, rapidly evolving receptors of innate and adaptive immunity. Annu. Rev. Immunol. 2002. 20: 217251.
  • 2
    Selvakumar, A., Steffens, U. and Dupont, B., NK cell receptor gene of the KIR family with two Ig domains but highest homology to KIR receptors with three Ig domains. Tissue Antigens 1996: 285295.
  • 3
    Yusa, S., Catina, T. L. and Campbell, K. S., SHP-1- and phosphotyrosine-independent inhibitory signaling by a killer cell Ig-like receptor cytoplasmic domain in human NK cells. J. Immunol. 2002. 168: 50475057.
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    Allan, D. S. J., Colonna, M., Lanier, L. L., Churakova, T. D., Abrams, J. S., Ellis, S. A., McMichael, A. J. and Braud, V. M., Tetrameric complexes of human histocompatibility leukocyte antigen (HLA)-G bind to peripheral blood myelomonocytic cells. J. Exp. Med. 1999. 189: 11491155.
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    Boyson, J. E., Erskine, R., Whitman, M. C., Chiu, M., Lau, J. M., Koopman, L. A., Valter, M. M. et al., Disulfide bond-mediated dimerization of HLA-G on the cell surface. Proc. Natl. Acad. Sci. USA 2002. 99: 1618016185.
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    Rajagopalan, S. and Long, E. O., A human histocompatibility leukocyte antigen (HLA)-G-specific receptor expressed on all natural killer cells. J. Exp. Med. 1999. 189: 10931100.
  • 7
    Cantoni, C., Verdiani, S., Falco, M., Pessino, A., Cilli, M., Conte, R., Pende, D. et al., p49, a putative HLA class I-specific inhibitory NK receptor belonging to the immunoglobulin superfamily [published erratum appears in Eur. J. Immunol. 1998, 28: 3398]. Eur. J. Immunol. 1998. 28: 19801990.
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    Ponte, M., Cantoni, C., Biassoni, R., Tradori-Cappai, A., Bentivoglio, G., Vitale, C., Bertone, S. et al., Inhibitory receptors sensing HLA-G1 molecules in pregnancy: Decidua-associated natural killer cells express LIR-1 and CD94/NKG2A and acquire p49, an HLA-G1-specific receptor [see comments]. Proc. Natl. Acad. Sci. USA 1999. 96: 56745679.
  • 9
    Yan, W. H. and Fan, L. A., Residues Met76 and Gln79 in HLA-G alpha1 domain involved in KIR2DL4 recognition. Cell Res. 2005. 15: 176182.
  • 10
    Rajagopalan, S., Bryceson, Y. T., Kuppusamy, S. P., Geraghty, D. E., Meer, A. V., Joosten, I. and Long, E. O., Activation of NK cells by an endocytosed receptor for soluble HLA-G. PLoS Biol. 2005. 4: e9.
  • 11
    Yu, Y. R., Tian, X. H., Wang, Y. and Feng, M. F., Rapid production of human KIR2DL4 extracellular domain and verification of its interaction with HLA-G. Biochemistry (Moscow) 2005. 71: S60S64.
  • 12
    Valiante, N. M., Uhrberg, M., Shilling, H. G., Lienert-Weidenbach, K., Arnett, K. L., D'Andrea, A., Phillips, J. H. et al., Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors. Immunity 1998. 7: 739751.
  • 13
    Husain, Z., Alper, C. A., Yunis, E. J. and Dubey, D. P., Complex expression of natural killer receptor genes in single natural killer cells. Immunology 2002. 106: 373380.
  • 14
    Goodridge, J. P., Witt, C. S., Christiansen, F. T. and Warren, H. S., KIR2DL4 (CD158d) genotype influences expression and function in NK cells. J. Immunol. 2003. 171: 17681774.
  • 15
    Kikuchi-Maki, A., Yusa, S., Catina, T. L. and Campbell, K. S., KIR2DL4 is an IL-2-regulated NK cell receptor that exhibits limited expression in humans but triggers strong IFN-gamma production. J. Immunol. 2003. 171: 34153425.
  • 16
    Witt, C. S., Martin, A. and Christiansen, F. T., Detection of KIR2DL4 alleles by sequencing and SSCP reveals a common allele with a shortened cytoplasmic tail. Tissue Antigens 2000. 56: 248257.
  • 17
    Witt, C. S., Whiteway, J. M., Warren, H. S., Barden, A., Rogers, M., Martin, A., Beilin, L. and Christiansen, F. T., Alleles of the KIR2DL4 receptor and their lack of association with pre-eclampsia. Eur. J. Immunol. 2002. 32: 1829.
  • 18
    Williams, F., Meenagh, A., Sleator, C. and Middleton, D., Investigation of killer cell immunoglobulinlike receptor gene diversity: I. KIR2DL4. Hum. Immunol. 2004. 65: 3138.
  • 19
    Gedil, M. A., Steiner, N. K. and Hurley, C. K., Genomic characterization of KIR2DL4 in families and unrelated individuals reveals extensive diversity in exon and intron sequences including a common frameshift variation occurring in several alleles. Tissue Antigens 2005. 65: 402418.
  • 20
    Zhu, F. M., Jiang, K., Lv, Q. F., He, J. and Yan, L. X., Investigation of killer cell immunoglobulin-like receptor KIR2DL4 diversity by sequence-based typing in Chinese population. Tissue Antigens 2006. 67: 214221.
  • 21
    Selvakumar, A., Steffens, U., Palanisamy, N., Chaganti, R. S. K. and Dupont, B., Genomic organisation and allelic polymorphism of the human killer cell inhibitory receptor gene KIR103. Tissue Antigens 1997. 49: 564573.
  • 22
    Rajagopalan, S., Fu, J. and Long, E. O., Cutting Edge: Induction of IFN-gamma production but not cytotoxicity by the killer cell Ig-like receptor KIR2DL4 (CD158d) in resting NK cells. J. Immunol. 2001. 167: 18771881.
  • 23
    Thimme, R., Oldach, D., Chang, K. M., Steiger, C., Ray, S. C. and Chisari, F. V., Determinants of viral clearance and persistence during acute hepatitis C virus infection. J. Exp. Med. 2001. 194: 13951406.
  • 24
    Koopman, L. A., Kopcow, H. D., Rybalov, B., Boyson, J. E., Orange, J. S., Schatz, F., Masch, R. et al., Human decidual natural killer cells are a unique NK cell subset with immunomodulatory potential. J. Exp. Med. 2003. 198: 12011212.
  • 25
    Kikuchi-Maki, A., Catina, T. L. and Campbell, K. S., Cutting Edge: KIR2DL4 transduces signals into human NK cells through association with the Fc receptor gamma protein. J. Immunol. 2005. 174: 38593863.
  • 26
    Chapman, T. L., Heikema, A. P., West, A. P., Jr. and Bjorkman, P. J., Crystal structure and ligand binding properties of the D1D2 region of the inhibitory receptor LIR-1 (ILT2). Immunity 2000. 13: 727736.
  • 27
    Le Friec, G., Gros, F., Sebti, Y., Guilloux, V., Pangault, C., Fauchet, R. and Amiot, L., Capacity of myeloid and plasmacytoid dendritic cells especially at mature stage to express and secrete HLA-G molecules. J. Leukoc. Biol. 2004. 76: 11251133.
  • 28
    Ishitani, A. and Geraghty, D. E., Alternative splicing of HLA-G transcripts yields proteins with primary structures resembling both class I and class II antigens. Proc. Natl. Acad. Sci. USA 1992. 89: 39473951.