SEARCH

SEARCH BY CITATION

  • 1
    Kennedy, M. K., Glaccum, M., Brown, S. N., Butz, E. A., Viney, J. L., Embers, M., Matsuki, N. et al., Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J. Exp. Med. 2000. 191: 771780.
  • 2
    Rodewald, H. R., Ogawa, M., Haller, C., Waskow, C. and DiSanto, J. P., Pro-thymocyte expansion by c-kit and the common cytokine receptor gamma chain is essential for repertoire formation. Immunity 1997. 6: 265272.
  • 3
    von Freeden-Jeffry, U., Vieira, P., Lucian, L. A., McNeil, T., Burdach, S. E. and Murray, R., Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J. Exp. Med. 1995. 181: 15191526.
  • 4
    Vosshenrich, C. A., Garcia-Ojeda, M. E., Samson-Villeger, S. I., Pasqualetto, V., Enault, L., Richard-Le Goff, O., Corcuff, E. et al., A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127. Nat. Immunol. 2006. 7: 12171224.
  • 5
    Vosshenrich, C. A., Ranson, T., Samson, S. I., Corcuff, E., Colucci, F., Rosmaraki, E. E. and Di Santo, J. P., Roles for common cytokine receptor gamma-chain-dependent cytokines in the generation, differentiation, and maturation of NK cell precursors and peripheral NK cells in vivo. J. Immunol. 2005. 174: 12131221.
  • 6
    Murray, P. J., The JAK-STAT signaling pathway: Input and output integration. J. Immunol. 2007. 178: 26232629.
  • 7
    Kovanen, P. E. and Leonard, W. J., Cytokines and immunodeficiency diseases: Critical roles of the gamma(c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways. Immunol. Rev. 2004. 202: 6783.
  • 8
    Kovanen, P. E., Rosenwald, A., Fu, J., Hurt, E. M., Lam, L. T., Giltnane, J. M., Wright, G. et al., Analysis of gamma c-family cytokine target genes. Identification of dual-specificity phosphatase 5 (DUSP5) as a regulator of mitogen-activated protein kinase activity in interleukin-2 signaling. J. Biol. Chem. 2003. 278: 52055213.
  • 9
    Opferman, J. T. and Korsmeyer, S. J., Apoptosis in the development and maintenance of the immune system. Nat. Immunol. 2003. 4: 410415.
  • 10
    von Freeden-Jeffry, U., Solvason, N., Howard, M. and Murray, R., The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression. Immunity 1997. 7: 147154.
  • 11
    Di Santo, J. P., Aifantis, I., Rosmaraki, E., Garcia, C., Feinberg, J., Fehling, H. J., Fischer, A. et al., The common cytokine receptor gamma chain and the pre-T cell receptor provide independent but critically overlapping signals in early alpha/beta T cell development. J. Exp. Med. 1999. 189: 563574.
  • 12
    Rodewald, H. R., Waskow, C. and Haller, C., Essential requirement for c-kit and common gamma chain in thymocyte development cannot be overruled by enforced expression of Bcl-2. J. Exp. Med. 2001. 193: 14311437.
  • 13
    Akashi, K., Kondo, M., von Freeden-Jeffry, U., Murray, R. and Weissman, I. L., Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell 1997. 89: 10331041.
  • 14
    Maraskovsky, E., O'Reilly, L. A., Teepe, M., Corcoran, L. M., Peschon, J. J. and Strasser, A., Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant RAG-1–/– mice. Cell 1997. 89: 10111019.
  • 15
    Li, W. Q., Jiang, Q., Khaled, A. R., Keller, J. R. and Durum, S. K., Interleukin-7 inactivates the pro-apoptotic protein Bad promoting T cell survival. J. Biol. Chem. 2004. 279: 2916029166.
  • 16
    Khaled, A. R., Li, W. Q., Huang, J., Fry, T. J., Khaled, A. S., Mackall, C. L., Muegge, K. et al., Bax deficiency partially corrects interleukin-7 receptor alpha deficiency. Immunity 2002. 17: 561573.
  • 17
    Opferman, J. T., Letai, A., Beard, C., Sorcinelli, M. D., Ong, C. C. and Korsmeyer, S. J., Development and maintenance of B and T lymphocytes requires antiapoptotic Mcl-1. Nature 2003. 426: 671676.
  • 18
    Kondo, M., Akashi, K., Domen, J., Sugamura, K. and Weissman, I. L., Bcl-2 rescues T lymphopoiesis, but not B or NK cell development, in common gamma chain-deficient mice. Immunity 1997. 7: 155162.
  • 19
    Ma, A., Koka, R. and Burkett, P., Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis. Annu. Rev. Immunol. 2006. 24: 657679.
  • 20
    Ranson, T., Vosshenrich, C. A., Corcuff, E., Richard, O., Muller, W. and Di Santo, J. P., IL-15 is an essential mediator of peripheral NK-cell homeostasis. Blood 2003. 101: 48874893.
  • 21
    Vella, A., Teague, T. K., Ihle, J., Kappler, J. and Marrack, P., Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: STAT6 is probably not required for the effect of IL-4. J. Exp. Med. 1997. 186: 325330.
  • 22
    Malek, T. R. and Bayer, A. L., Tolerance, not immunity, crucially depends on IL-2. Nat. Rev. Immunol. 2004. 4: 665674.
  • 23
    Lantz, O., Grandjean, I., Matzinger, P. and Di Santo, J. P., Gamma chain required for naive CD4+ T cell survival but not for antigen proliferation. Nat. Immunol. 2000. 1: 5458.
  • 24
    Grandjean, I., Duban, L., Bonney, E. A., Corcuff, E., Di Santo, J. P., Matzinger, P. and Lantz, O., Are major histocompatibility complex molecules involved in the survival of naive CD4+ T cells? J. Exp. Med. 2003. 198: 10891102.
  • 25
    Rathmell, J. C., Farkash, E. A., Gao, W. and Thompson, C. B., IL-7 enhances the survival and maintains the size of naive T cells. J. Immunol. 2001. 167: 68696876.
  • 26
    Seddon, B., Tomlinson, P. and Zamoyska, R., Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells. Nat. Immunol. 2003. 4: 680686.
  • 27
    Strasser, A., Harris, A. W. and Cory, S., Bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell 1991. 67: 889899.
  • 28
    Smith, K. A., Interleukin-2: Inception, impact, and implications. Science 1988. 240: 11691176.
  • 29
    Cantrell, D., Protein kinase B (Akt) regulation and function in T lymphocytes. Semin. Immunol. 2002. 14: 1926.
  • 30
    Plas, D. R. and Thompson, C. B., Akt-dependent transformation: There is more to growth than just surviving. Oncogene 2005. 24: 74357442.
  • 31
    Jones, R. G., Parsons, M., Bonnard, M., Chan, V. S., Yeh, W. C., Woodgett, J. R. and Ohashi, P. S., Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo. J. Exp. Med. 2000. 191: 17211734.
  • 32
    Rathmell, J. C., Elstrom, R. L., Cinalli, R. M. and Thompson, C. B., Activated Akt promotes increased resting T cell size, CD28-independent T cell growth, and development of autoimmunity and lymphoma. Eur. J. Immunol. 2003. 33: 22232232.
  • 33
    Hagenbeek, T. J., Naspetti, M., Malergue, F., Garcon, F., Nunes, J. A., Cleutjens, K. B., Trapman, J. et al., The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and pre-TCR-mediated signaling. J. Exp. Med. 2004. 200: 883894.
  • 34
    Na, S. Y., Patra, A., Scheuring, Y., Marx, A., Tolaini, M., Kioussis, D., Hemmings, B. A. et al., Constitutively active protein kinase B enhances Lck and ERK activities and influences thymocyte selection and activation. J. Immunol. 2003. 171: 12851296.
  • 35
    Rathmell, J. C., Vander Heiden, M. G., Harris, M. H., Frauwirth, K. A. and Thompson, C. B., In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability. Mol. Cell 2000. 6: 683692.
  • 36
    Tan, J. T., Dudl, E., LeRoy, E., Murray, R., Sprent, J., Weinberg, K. I. and Surh, C. D., IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc. Natl. Acad. Sci. USA 2001. 98: 87328737.
  • 37
    Nakajima, H., Shores, E. W., Noguchi, M. and Leonard, W. J., The common cytokine receptor gamma chain plays an essential role in regulating lymphoid homeostasis. J. Exp. Med. 1997. 185: 189195.
  • 38
    Sharara, L. I., Andersson, A., Guy-Grand, D., Fischer, A. and DiSanto, J. P., Deregulated TCR alpha beta T cell population provokes extramedullary hematopoiesis in mice deficient in the common gamma chain. Eur. J. Immunol. 1997. 27: 990998.
  • 39
    Schluns, K. S., Kieper, W. C., Jameson, S. C. and Lefrancois, L., Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat. Immunol. 2000. 1: 426432.
  • 40
    Pallard, C., Stegmann, A. P., van Kleffens, T., Smart, F., Venkitaraman, A. and Spits, H., Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors. Immunity 1999. 10: 525535.
  • 41
    Ciofani, M. and Zuniga-Pflucker, J. C., Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism. Nat. Immunol. 2005. 6: 881888.
  • 42
    Yu, Q., Erman, B., Bhandoola, A., Sharrow, S. O. and Singer, A., In vitro evidence that cytokine receptor signals are required for differentiation of double positive thymocytes into functionally mature CD8+ T cells. J. Exp. Med. 2003. 197: 475487.
  • 43
    Seddon, B. and Zamoyska, R., TCR and IL-7 receptor signals can operate independently or synergize to promote lymphopenia-induced expansion of naive T cells. J. Immunol. 2002. 169: 37523759.