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    Reiner, S. L., Development in motion: Helper T cells at work. Cell 2007. 129: 3336.
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    Ivanov, I. I., McKenzie, B. S., Zhou, L., Tadokoro, C. E., Lepelley, A., Lafaille, J. J., Cua, D. J. and Littman, D. R., The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 2006. 126: 11211133.
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    Fontenot, J. D., Gavin, M. A. and Rudensky, A. Y., Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 2003. 4: 330336.
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    Bettelli, E., Carrier, Y., Gao, W., Korn, T., Strom, T. B., Oukka, M., Weiner, H. L. and Kuchroo, V. K., Reciprocal developmental pathways for the generation of pathogenic effector Th17 and regulatory T cells. Nature 2006. 441: 235238.
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    Mangan, P. R., Harrington, L. E., O'Quinn, D. B., Helms, W. S., Bullard, D. C., Elson, C. O., Hatton, R. D. et al., Transforming growth factor-beta induces development of the T(H)17 lineage. Nature 2006. 441: 231234.
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    Osanai, M., Nishikiori, N., Murata, M., Chiba, H., Kojima, T. and Sawada, N., Cellular retinoic acid bioavailability determines epithelial integrity: Role of retinoic acid receptor alpha agonists in colitis. Mol. Pharmacol. 2007. 71: 250258.
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    Miyagawa, N., Homma, T., Kagechika, H., Shudo, K. and Nagai, H., Effect of synthetic retinoid, TAC-101, on experimental autoimmune disease. Pharmacology 2003. 67: 2131.
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    Zunino, S. J., Storms, D. H. and Stephensen, C. B., Diets rich in polyphenols and vitamin A inhibit the development of type I autoimmune diabetes in nonobese diabetic mice. J. Nutr. 2007. 137: 12161221.
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    Racke, M. K., Burnett, D., Pak, S. H., Albert, P. S., Cannella, B., Raine, C. S., McFarlin, D. E. and Scott, D. E., Retinoid treatment of experimental allergic encephalomyelitis. IL-4 production correlates with improved disease course. J. Immunol. 1995. 154: 450458.
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    Reifen, R., Nur, T., Ghebermeskel, K., Zaiger, G., Urizky, R. and Pines, M., Vitamin A deficiency exacerbates inflammation in a rat model of colitis through activation of nuclear factor-kappaB and collagen formation. J. Nutr. 2002. 132: 27432747.
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    Long, K. Z., Santos, J. I., Rosado, J. L., Lopez-Saucedo, C., Thompson-Bonilla, R., Abonce, M., DuPont, H. L. et al., Impact of vitamin A on selected gastrointestinal pathogen infections and associated diarrheal episodes among children in Mexico City, Mexico. J. Infect. Dis. 2006. 194: 12171225.
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    Orfanos, C. E., Zouboulis, C. C., Almond-Roesler, B. and Geilen, C. C., Current use and future potential role of retinoids in dermatology. Drugs 1997. 53: 358388.
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    Iwata, M., Hirakiyama, A., Eshima, Y., Kagechika, H., Kato, C. and Song, S. Y., Retinoic acid imprints gut-homing specificity on T cells. Immunity 2004. 21: 527538.
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    Spanjaard, R. A., Ikeda, M., Lee, P. J., Charpentier, B., Chin, W. W. and Eberlein, T. J., Specific activation of retinoic acid receptors (RARs) and retinoid X receptors reveals a unique role for RARgamma in induction of differentiation and apoptosis of S91 melanoma cells. J. Biol. Chem. 1997. 272: 1899018999.
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    Kagechika, H., Novel synthetic retinoids and separation of the pleiotropic retinoidal activities. Curr. Med. Chem. 2002. 9: 591608.
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    Apfel, C., Bauer, F., Crettaz, M., Forni, L., Kamber, M., Kaufmann, F., LeMotte, P. et al., A retinoic acid receptor alpha antagonist selectively counteracts retinoic acid effects. Proc. Natl. Acad. Sci. USA 1992. 89: 71297133.
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    Lee, I. H., Lee, J. H., Lee, M. J., Lee, S. Y. and Kim, I. S., Involvement of CCAAT/enhancer-binding protein alpha in haptoglobin gene expression by all-trans-retinoic acid. Biochem. Biophys. Res. Commun. 2002. 294: 956961.
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    Mantel, P. Y., Ouaked, N., Ruckert, B., Karagiannidis, C., Welz, R., Blaser, K. and Schmidt-Weber, C. B., Molecular mechanisms underlying FoxP3 induction in human T cells. J. Immunol. 2006. 176: 35933602.
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    Mucida, D., Park, Y., Kim, G., Turovskaya, O., Scott, I., Kronenberg, M. and Cheroutre, H., Reciprocal Th17 and regulatory T cell differentiation mediated by retinoic acid. Science 2007. 317: 256260.
  • 20
    Mullen, A. C., High, F. A., Hutchins, A. S., Lee, H. W., Villarino, A. V., Livingston, D. M., Kung, A. L. et al., Role of T-bet in commitment of Th1 cells before IL-12-dependent selection. Science 2001. 292: 19071910.