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  • 1
    Wymann, M. P. and Pirola, L., Structure and function of phosphoinositide 3-kinases. Biochim. Biophys. Acta 1998 1436: 127150.
  • 2
    Jones, G. E., Prigmore, E., Calvez, R., Hogan, C., Dunn, G. A., Hirsch, E., Wymann, M. P. and Ridley, A. J., Requirement for PI 3-kinase gamma in macrophage migration to MCP-1 and CSF-1. Exp. Cell Res. 2003 290: 120131.
  • 3
    Sadhu, C., Masinovsky, B., Dick, K., Sowell, C. G. and Staunton, D. E., Essential role of phosphoinositide 3-kinase δ in neutrophil directional movement. J. Immunol. 2003 170: 26472654.
  • 4
    Puri, K. D., Doggett, T. A., Douangpanya, J., Hou, Y., Tino, W. T., Wilson, T., Graf, T. et al., Mechanisms and implications of phosphoinositide 3-kinase delta in promoting neutrophil trafficking into inflamed tissue. Blood 2004 103: 34483456.
  • 5
    Hirsch, E., Katanaev, V. L., Garlanda, C., Azzolino, O., Pirola, L., Silengo, L., Sozzani, S. et al., Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. Science 2000 287: 10491053.
  • 6
    Sasaki, T., Irie-Sasaki, J., Jones, R. G., Oliveira-dos-Santos, A. J., Stanford, W. L., Bolon, B., Wakeham, A. et al., Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration. Science 2000 287: 10401046.
  • 7
    Puri, K. D., Doggett, T. A., Huang, C.Y., Douangpanya, J., Hayflick, J. S., Turner, M., Penninger, J. and Diacovo, T. G., The role of endothelial PI3Kgamma activity in neutrophil trafficking. Blood 2005 106: 150157.
  • 8
    Bilancio, A., Okkenhaug, K., Camps, M., Emery, J. L., Ruckle, T., Rommel, C. and Vanhaesebroeck, B., Key role of the p110delta isoform of PI3K in B-cell antigen and IL-4 receptor signaling: comparative analysis of genetic and pharmacologic interference with p110delta function in B cells. Blood 2006 107: 642650.
  • 9
    Camps, M., Ruckle, T., Ji, H., Ardissone, V., Rintelen, F., Shaw, J., Ferrandi, C. et al., Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis. Nat. Med. 2005 11: 936943.
  • 10
    Jou, S. T., Carpino, N., Takahashi, Y., Piekorz, R., Chao, J. R., Carpino, N., Wang, D. and Ihle, J. N., Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex. Mol. Cell. Biol. 2002 22: 85808591.
  • 11
    Clayton, E., Bardi, G., Bell, S. E., Chantry, D., Downes, C. P., Gray, A., Humphries, L. A. et al., A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation. J. Exp. Med. 2002 196: 753763.
  • 12
    Vanhaesebroeck, B., Ali, K., Bilancio, A., Geering, B. and Foukas, L. C., Signalling by PI3K isoforms: Insights from gene-targeted mice. Trends Biochem. Sci. 2005 30: 194204.
  • 13
    Liu, L., Puri, K. D., Penninger, J. M. and Kubes, P., Leukocyte PI3Kgamma and PI3Kdelta have temporally distinct roles for leukocyte recruitment in vivo. Blood 2007 110: 11911198.
  • 14
    Pinho, V., de Castro Russo, R., Amaral, F.A., de Sousa, L. P., Barsante, M. M., de Souza, D. G., Alves-Filho, J. C. et al., Tissue- and stimulus-dependent role of phosphatidylinositol 3-kinase isoforms for neutrophil recruitment induced by chemoattractants in vivo. J. Immunol. 2007 179: 78917898.
  • 15
    Rommel, C., Camps, M. and Ji, H., PI3K delta and PI3K gamma: Partners in crime in inflammation in rheumatoid arthritis and beyond? Nat. Rev. Immunol. 2007 7: 191201.
  • 16
    Kyburz, D. and Corr, M., The KRN mouse model of inflammatory arthritis. Springer Semin. Immunopathol. 2003 25: 7990.
  • 17
    Maccioni, M., Zeder-Lutz, G., Huang, H., Ebel, C., Gerber, P., Hergueux, J., Marchal, P. et al., Arthritogenic monoclonal antibodies from K/BxN mice. J. Exp. Med. 2002 195: 10711077.
  • 18
    Korganow, A. S., Ji, H., Mangialaio, S., Duchatelle, V., Pelanda, R., Martin, T., Degott, C. et al., From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins. Immunity 1999 10: 451461.
  • 19
    Zhou, J. S., Xing, W., Friend, D. S., Austen, K. F. and Katz, H. R., Mast cell deficiency in Kit(W-sh) mice does not impair antibody-mediated arthritis. J. Exp. Med. 2007 204: 27972802.
  • 20
    Chen, M., Lam, B. K., Kanaoka, Y., Nigrovic, P. A., Audoly, L. P., Austen, K. F. and Lee, D. M., Neutrophil-derived leukotriene B4 is required for inflammatory arthritis. J. Exp. Med. 2006 203: 837842.
  • 21
    Kim, N. D., Chou, R. C., Seung, E., Tager, A. M. and Luster, A. D., A unique requirement for the leukotriene B4 receptor BLT1 for neutrophil recruitment in inflammatory arthritis. J. Exp. Med. 2006 203: 829835.
  • 22
    Wipke, B. T. and Allen, P. M., Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis . J. Immunol. 2001 167: 16011608.
  • 23
    Swat, W., Montgrain, V., Doggett, T. A., Douangpanya, J., Puri, K., Vermi, W. and Diacovo, T. G., Essential role of PI3Kdelta and PI3Kgamma in thymocyte survival. Blood 2006 107: 24152422.
  • 24
    Tassi, I., Cella, M., Gilfillan, S., Turnbull, I., Diacovo, T. G., Penninger, J. M. and Colonna, M., p110gamma and p110delta phosphoinositide 3-kinase signaling pathways synergize to control development and functions of murine NK cells. Immunity 2007 27: 214227.
  • 25
    Webb, L. M., Vigorito, E., Wymann, M. P., Hirsch, E. and Turner, M., Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase. J. Immunol. 2005 175: 27832787.
  • 26
    Foy, D. S. and Ley, K., Intercellular adhesion molecule-1 is required for chemoattractant-induced leukocyte adhesion in resting, but not inflamed, venules in vivo. Microvasc. Res. 2000 60: 249260.
  • 27
    Ferguson, G. J., Milne, L., Kulkarni, S., Sasaki, T., Walker, S., Andrews, S., Crabbe, T. et al., PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis. Nat. Cell Biol. 2007 9: 8691.
  • 28
    Condliffe, A. M., Davidson, K., Anderson, K. E., Ellson, C. D., Crabbe, T., Okkenhaug, K., Vanhaesebroeck, B. et al., Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils. Blood 2005 106: 14321440.
  • 29
    Boulven, I., Levasseur, S., Marois, S., Paré, G., Rollet-Labelle, E. and Naccache, P. H., Class IA phosphatidylinositide 3-kinases, rather than p110 gamma, regulate formyl-methionyl-leucyl-phenylalanine-stimulated chemotaxis and superoxide production in differentiated neutrophil-like PLB-985 cells. J. Immunol. 2006 176: 76217627.
  • 30
    Eliason, J. L., Hannawa, K. K., Ailawadi, G., Sinha, I., Ford, J. W., Deogracias, M. P., Roelofs, K. J. et al., Neutrophil depletion inhibits experimental abdominal aortic aneurysm formation. Circulation 2005 112: 232240.
  • 31
    Bolon, B., Morony, S., Cheng, Y., Hu, Y. L. and Feige, U., Osteoclast numbers in Lewis rats with adjuvant-induced arthritis: Identification of preferred sites and parameters for rapid quantitative analysis. Vet. Pathol. 2004 41: 3036.