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  • 1
    Medzhitov, R. and Janeway, C. A., Jr., Decoding the patterns of self and nonself by the innate immune system. Science 2002. 296: 298300.
  • 2
    Maloy, K. J. and Powrie, F., Regulatory T cells in the control of immune pathology. Nat. Immunol. 2001. 2: 816822.
  • 3
    Sakaguchi, S., Sakaguchi, N., Shimizu, J., Yamazaki, S., Sakihama, T., Itoh, M., Kuniyasu, Y. et al., Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol. Rev. 2001. 182: 1832.
  • 4
    Baecher-Allan, C. and Hafler, D. A., Human regulatory T cells and their role in autoimmune disease. Immunol. Rev. 2006. 212: 203216.
  • 5
    Fontenot, J. D., Gavin, M. A. and Rudensky, A. Y., Foxp3 programs the development and function of CD4+ CD25+ regulatory T cells. Nat. Immunol. 2003. 4: 330336.
  • 6
    Hori, S., Nomura, T. and Sakaguchi, S., Control of regulatory T cell development by the transcription factor Foxp3. Science 2003. 299: 10571061.
  • 7
    Takahashi, T., Kuniyasu, Y., Toda, M., Sakaguchi, N., Itoh, M., Iwata, M., Shimizu, J. and Sakaguchi, S., Immunologic self-tolerance maintained by CD25+ CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int. Immunol. 1998. 10: 19691980.
  • 8
    Coombes, J. L., Robinson, N. J., Maloy, K. J., Uhlig, H. H. and Powrie, F., Regulatory T cells and intestinal homeostasis. Immunol. Rev. 2005. 204: 184194.
  • 9
    Singh, B., Read, S., Asseman, C., Malmstrom, V., Mottet, C., Stephens, L. A., Stepankova, R. et al., Control of intestinal inflammation by regulatory T cells. Immunol. Rev. 2001. 182: 190200.
  • 10
    Powrie, F., T cells in inflammatory bowel disease: protective and pathogenic roles. Immunity 1995. 3: 171174.
  • 11
    Blumberg, R. S., Saubermann, L. J. and Strober, W., Animal models of mucosal inflammation and their relation to human inflammatory bowel disease. Curr. Opin. Immunol. 1999. 11: 648656.
  • 12
    Read, S., Malmstrom, V. and Powrie, F., Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J. Exp. Med. 2000. 192: 295302.
  • 13
    Aseffa, A., Gumy, A., Launois, P., MacDonald, H. R., Louis, J. A. and Tacchini-Cottier, F., The early IL-4 response to Leishmania major and the resulting Th2 cell maturation steering progressive disease in BALB/c mice are subject to the control of regulatory CD4+ CD25+ T cells. J. Immunol. 2002. 169: 32323241.
  • 14
    Belkaid, Y., Piccirillo, C. A., Mendez, S., Shevach, E. M. and Sacks, D. L., CD4+ CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature 2002. 420: 502507.
  • 15
    Hisaeda, H., Maekawa, Y., Iwakawa, D., Okada, H., Himeno, K., Kishihara, K., Tsukumo, S. and Yasutomo, K., Escape of malaria parasites from host immunity requires CD4+ CD25+ regulatory T cells. Nat. Med. 2004. 10: 2930.
  • 16
    Hori, S., Carvalho, T. L. and Demengeot, J., CD25+ CD4+ regulatory T cells suppress CD4+ T cell-mediated pulmonary hyperinflammation driven by Pneumocystis carinii in immunodeficient mice. Eur. J. Immunol. 2002. 32: 12821291.
  • 17
    Lundgren, A., Stromberg, E., Sjoling, A., Lindholm, C., Enarsson, K., Edebo, A., Johnsson, E. et al., Mucosal FOXP3-expressing CD4+ CD2 5high regulatory T cells in Helicobacter pylori-infected patients. Infect. Immun. 2005. 73: 523531.
  • 18
    Seifarth, C., Funk, A., Reich, K., Dahne, I., Classen, M. and Deusch, K., Selective increase of CD4+ and CD25+ T cells but not of gamma delta T cells in H. pylori associated gastritis. Adv. Exp. Med. Biol. 1995. 371B: 931934.
  • 19
    Stromberg, E., Lundgren, A., Edebo, A., Lundin, S., Svennerholm, A. M. and Lindholm, C., Increased frequency of activated T-cells in the Helicobacter pylori-infected antrum and duodenum. FEMS Immunol. Med. Microbiol. 2003. 36: 159168.
  • 20
    Malaty, H. M. and Graham, D. Y., Importance of childhood socioeconomic status on the current prevalence of Helicobacter pylori infection. Gut 1994. 35: 742745.
  • 21
    Suerbaum, S. and Michetti, P., Helicobacter pylori infection. N. Engl. J. Med. 2002. 347: 11751186.
  • 22
    Fan, X. J., Chua, A., Shahi, C. N., McDevitt, J., Keeling, P. W. and Kelleher, D., Gastric T lymphocyte responses to Helicobacter pylori in patients with H. pylori colonisation. Gut 1994. 35: 13791384.
  • 23
    Karttunen, R., Blood lymphocyte proliferation, cytokine secretion and appearance of T cells with activation surface markers in cultures with Helicobacter pylori. Comparison of the responses of subjects with and without antibodies to H. pylori. Clin. Exp. Immunol. 1991. 83: 396400.
  • 24
    Anderson, K., Czinn, S., Redline, R. and Blanchard, T., Induction of CTLA-4 mediated anergy contributes to persistent colonization in the murine model of gastric Helicobacter pylori infection. J. Immunol. 2006. 176: 53065313.
  • 25
    Rahn, W., Redline, R. W. and Blanchard, T. G., Molecular analysis of Helicobacter pylori-associated gastric inflammation in naive versus previously immunized mice. Vaccine 2004. 23: 807818.
  • 26
    Rad, R., Brenner, L., Bauer, S., Schwendy, S., Layland, L., da Costa, C. P., Reindl, W. et al., CD25+/Foxp3+ T cells regulate gastric inflammation and Helicobacter pylori colonization in vivo. Gastroenterology 2006. 131: 525537.
  • 27
    Raghavan, S., Fredriksson, M., Svennerholm, A. M., Holmgren, J. and Suri-Payer, E., Absence of CD4+CD25+ regulatory T cells is associated with a loss of regulation leading to increased pathology in Helicobacter pylori-infected mice. Clin. Exp. Immunol. 2003. 132: 393400.
  • 28
    Lundgren, A., Suri-Payer, E., Enarsson, K., Svennerholm, A. M. and Lundin, B. S., Helicobacter pylori-specific CD4+ CD25 high regulatory T cells suppress memory T-cell responses to H. pylori in infected individuals. Infect. Immun. 2003. 71: 17551762.
  • 29
    Malfitano, A. M., Cahill, R., Mitchell, P., Frankel, G., Dougan, G., Bifulco, M., Lombardi, G. et al., Helicobacter pylori has stimulatory effects on naive T cells. Helicobacter 2006. 11: 2130.
  • 30
    Ermak, T. H., Giannasca, P. J., Nichols, R., Myers, G. A., Nedrud, J., Weltzin, R., Lee, C. K. et al., Immunization of mice with urease vaccine affords protection against Helicobacter pylori infection in the absence of antibodies and is mediated by MHC class II-restricted responses. J. Exp. Med. 1998. 188: 22772288.
  • 31
    Garhart, C. A., Redline, R. W., Nedrud, J. G. and Czinn, S. J., Clearance of Helicobacter pylori infection and resolution of postimmunization gastritis in a kinetic study of prophylactically immunized mice. Infect. Immun. 2002. 70: 35293538.
  • 32
    Cuenca, R., Blanchard, T. G., Czinn, S. J., Nedrud, J. G., Monath, T. P., Lee, C. K. and Redline, R. W., Therapeutic immunization against Helicobacter mustelae in naturally infected ferrets. Gastroenterology 1996. 110: 17701775.
  • 33
    Doidge, C., Crust, I., Lee, A., Buck, F., Hazell, S. and Manne, U., Therapeutic immunisation against Helicobacter infection. Lancet 1994. 343: 914915.
  • 34
    Raghavan, S., Suri-Payer, E. and Holmgren, J., Antigen-specific in vitro suppression of murine Helicobacter pylori-reactive immunopathological T cells by CD4CD25 regulatory T cells. Scand. J. Immunol. 2004. 60: 8288.
  • 35
    Harris, P. R., Wright, S. W., Serrano, C., Riera, F., Duarte, I., Torres, J., Pena, A. et al., Helicobacter pylori gastritis in children is associated with a regulatory T-cell response. Gastroenterology 2008. 134: 491499.
  • 36
    Eaton, K. A., Mefford, M. and Thevenot, T., The role of T cell subsets and cytokines in the pathogenesis of Helicobacter pylori gastritis in mice. J. Immunol. 2001. 166: 74567461.
  • 37
    Eaton, K. A. and Mefford, M. E., Cure of Helicobacter pylori infection and resolution of gastritis by adoptive transfer of splenocytes in mice. Infect. Immun. 2001. 69: 10251031.
  • 38
    Eaton, K. A., Ringler, S. R. and Danon, S. J., Murine splenocytes induce severe gastritis and delayed-type hypersensitivity and suppress bacterial colonization in Helicobacter pylori-infected SCID mice. Infect. Immun. 1999. 67: 45944602.
  • 39
    Mottet, C., Uhlig, H. H. and Powrie, F., Cutting edge: cure of colitis by CD4+ CD25+ regulatory T cells. J. Immunol. 2003. 170: 39393943.
  • 40
    Michetti, P., Kreiss, C., Kotloff, K. L., Porta, N., Blanco, J. L., Bachmann, D., Herranz, M. et al., Oral immunization with urease and Escherichia coli heat-labile enterotoxin is safe and immunogenic in Helicobacter pylori-infected adults. Gastroenterology 1999. 116: 804812.
  • 41
    Lee, C. W., Rao, V. P., Rogers, A. B., Ge, Z., Erdman, S. E., Whary, M. T. and Fox, J. G., Wild-type and interleukin-10-deficient regulatory T cells reduce effector T-cell-mediated gastroduodenitis in Rag2/ mice, but only wild-type regulatory T cells suppress Helicobacter pylori gastritis. Infect. Immun. 2007. 75: 26992707.
  • 42
    Beswick, E. J., Pinchuk, I. V., Das, S., Powell, D. W. and Reyes, V. E., B7-H1 Expression on gastric epithelial cells after Helicobacter pylori exposure promotes the development of CD4+ CD25+ FoxP3+ regulatory T cells. Infect. Immun. 2007. 75: 43344341.
  • 43
    Ismail, H. F., Fick, P., Zhang, J., Lynch, R. G. and Berg, D. J., Depletion of neutrophils in IL-10(−/−) mice delays clearance of gastric Helicobacter infection and decreases the Th1 immune response to Helicobacter. J. Immunol. 2003. 170: 37823789.
  • 44
    Matsumoto, Y., Blanchard, T. G., Drakes, M. L., Basu, M., Redline, R. W., Levine, A. D. and Czinn, S. J., Eradication of Helicobacter pylori and resolution of gastritis in the gastric mucosa of IL-10-deficient mice. Helicobacter 2005. 10: 407415.
  • 45
    Lee, A., O'Rourke, J., De Ungria, M. C., Robertson, B., Daskalopoulos, G. and Dixon, M. F., A standardized mouse model of Helicobacter pylori infection: introducing the Sydney strain. Gastroenterology 1997. 112: 13861397.
  • 46
    Blanchard, T. G., Czinn, S. J., Redline, R. W., Sigmund, N., Harriman, G. and Nedrud, J. G., Antibody-independent protective mucosal immunity to gastric Helicobacter infection in mice. Cell. Immunol. 1999. 191: 7480.
  • 47
    Gottwein, J. M., Blanchard, T. G., Targoni, O. S., Eisenberg, J. C., Zagorski, B. M., Redline, R. W., Nedrud, J. G. et al., Protective anti-Helicobacter immunity is induced with aluminum hydroxide or complete Freund's adjuvant by systemic immunization. J. Infect. Dis. 2001. 184: 308314.